PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30408535-15	2019	Treatment with saponin rich fraction of A. lebbeck increased levels of Caspases-3 (optical density of 0.24 at 450 nm) and Caspase-8 (optical density of 0.31 at 450 nm) as compared to staurosporine (optical density of 2.47 and 2.65 for caspases-3 and -8 respectively at 450 nm).	Saponins	15-22	caspase 8	Homo sapiens	122-131	
16183855-0	2005	Apoptosis induced by a new member of saponin family is mediated through caspase-8-dependent cleavage of Bcl-2.	Saponins	37-44	caspase 8	Homo sapiens	72-81	
14761678-0	2004	A ginseng saponin metabolite-induced apoptosis in HepG2 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and Bid cleavage.	Saponins	10-17	caspase 8	Homo sapiens	122-131	
26295969-6	2015	Quantitative PCR and Western Blot analysis showed that the two saponins significantly increased mRNA expression of FADD and BID as well as induced caspase-8 via increased of procaspase-8 processing in the treated cells.	Saponins	63-71	caspase 8	Homo sapiens	147-156