PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23246638-8 2013 Moreover the antipsychotics, haloperidol and risperidone, were able to inhibit the secretion of S100B following IL-6 stimulation in C6 glioma cells. Risperidone 45-56 interleukin 6 Homo sapiens 112-116 32121312-6 2020 Risperidone and haloperidol both reduced the levels of IL-1alpha, IL-1beta, IL-2, and IL-17, and increased the levels of IL-6, IL-10, INF-gamma, and TNF-alpha. Risperidone 0-11 interleukin 6 Homo sapiens 121-125 29902518-5 2018 Risperidone showed an anti-inflammatory activity, decreasing the release of tumor necrosis factor alpha (TNF-alpha), interleukins 1beta (IL-1 beta) and 6 (IL-6), and increasing interleukin 10 (IL-10). Risperidone 0-11 interleukin 6 Homo sapiens 155-159 29558759-5 2017 Thus, the main aim of this clinical trial study was to determine the effects of treatment with risperidone and quetiapine, as antipsychotic drugs, with and without vitamin B12 on the psychotic symptoms of AD patients and the expression of IL-6, IL-8, tumor growth factor (TGF)-beta, tumor necrosis factor (TNF)-alpha, and endothelin (ET)-1). Risperidone 95-106 interleukin 6 Homo sapiens 239-243 26491028-9 2016 IL-6 levels significantly increased the risperidone-induced expression of AKT1, DICER1, DROSHA, and COMT mRNA. Risperidone 40-51 interleukin 6 Homo sapiens 0-4 27337797-5 2015 After treating the schizophrenics with the neuroleptic risperidone for 6 months, the serum levels of HMGB1, IL-1beta, TNF-alpha and IL-6 were decreased. Risperidone 55-66 interleukin 6 Homo sapiens 132-136 26491028-12 2016 Increased IL-6 levels may prime the expression of genes (AKT1, DICER1, DROSHA, and COMT) in response to risperidone, suggesting that cytokine x treatment x gene interactions may improve cell function profiles. Risperidone 104-115 interleukin 6 Homo sapiens 10-14 23981042-6 2013 Also, that APDs inhibited the production of LPS-stimulated macrophages IL-6 and IL-8 suggests that risperidone and clozapine may inhibit inflammation. Risperidone 99-110 interleukin 6 Homo sapiens 71-75 15886721-11 2005 In all, 12 weeks of risperidone treatment significantly decreased elevated cortisol and improved negative symptoms, but produced similar effects on IL-2 and IL-6 as well as on positive symptoms compared to haloperidol. Risperidone 20-31 interleukin 6 Homo sapiens 157-161 22154580-7 2012 Risperidone increased the production of IL-10 and MDC as well as the proinflammatory cytokines, such as IL-6, IL-8, and TNF-alpha, but decreased the production of IP-10 and IL-12. Risperidone 0-11 interleukin 6 Homo sapiens 104-108 15567770-4 2004 RESULT: In patients treated with risperidone, the levels of serum IL-6 and IL-2 after 4 weeks, TNFalpha after 8 weeks, and IL-18 after 6 months were all significantly lowered in comparison with the pretreatment levels (P<0.01 or 0.05). Risperidone 33-44 interleukin 6 Homo sapiens 66-70 15567770-12 2004 CONCLUSION: Clozapine and risperidone have similar immunosuppression actions and may affect serum IL-6 levels in patients with paranoid schizophrenia, in the psychopathology of which the cytokines play their roles of various importance. Risperidone 26-37 interleukin 6 Homo sapiens 98-102