PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24488604-3 2014 In this study, TC was found to significantly inhibit hypoxia-induced cytotoxicity as well as the release of proinflammatory cytokines, including IL-1beta, TNF-alpha, and IL-6, through activation of BV2 microglia following hypoxic exposure (1 % O2, 24 h). caryophyllene 15-17 interleukin 1 beta Homo sapiens 145-153 23734999-6 2013 By contrast, treatments with beta-caryophyllene dose-dependently inhibited mRNA expression of inducible nitric oxide synthetase, interleukin (IL)-1beta, IL-6, and cyclooxygenase 2 in C6 microglial cells, and decreased the level of nitric oxide and prostaglandin E2 at a 100 muM concentration. caryophyllene 29-47 interleukin 1 beta Homo sapiens 129-151 30620895-5 2019 KEY FINDINGS: The protective effects of BCP on LPS-induced microglia imbalance is provided by the M2 healing phenotype of microglia, releasing the anti-inflammatory (IL-10, Arg-1, and urea) and anti-oxidant (GSH) parameters and reducing the inflammatory (IL-1beta, TNF-alpha, PGE2, iNOS and NO) and oxidative (ROS) biomarkers. caryophyllene 40-43 interleukin 1 beta Homo sapiens 255-263