PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30343038-1 2019 Beta-caryophyllene (BCP) is a phytocannabinoid possessing selective agonistic activity to cannabinoid type-2 receptors (CB2R) and peroxisome proliferator-activated receptors-alpha (PPAR-alpha). caryophyllene 20-23 peroxisome proliferator activated receptor alpha Rattus norvegicus 181-191 30343038-1 2019 Beta-caryophyllene (BCP) is a phytocannabinoid possessing selective agonistic activity to cannabinoid type-2 receptors (CB2R) and peroxisome proliferator-activated receptors-alpha (PPAR-alpha). caryophyllene 0-18 peroxisome proliferator activated receptor alpha Rattus norvegicus 181-191 29402275-7 2018 In the frontal cortex, BCP further prevented activation of the endocannabinoid system (ECS), spared the docosahexaenoic acid (DHA), appeared to prevent the increase of cyclooxygenase-2 and increased the peroxisome-proliferator activated receptor-alpha (PPAR-alpha) protein levels, while, in plasma, BCP induced the reduction of arachidonoylethanolamide (AEA) levels as compared to vehicle-treated rats. caryophyllene 23-26 peroxisome proliferator activated receptor alpha Rattus norvegicus 203-251 29402275-7 2018 In the frontal cortex, BCP further prevented activation of the endocannabinoid system (ECS), spared the docosahexaenoic acid (DHA), appeared to prevent the increase of cyclooxygenase-2 and increased the peroxisome-proliferator activated receptor-alpha (PPAR-alpha) protein levels, while, in plasma, BCP induced the reduction of arachidonoylethanolamide (AEA) levels as compared to vehicle-treated rats. caryophyllene 23-26 peroxisome proliferator activated receptor alpha Rattus norvegicus 253-263 29402275-8 2018 CONCLUSIONS: Collectively, the pre-treatment with BCP, likely acting as agonist for CB2 and PPAR-alpha receptors, modulates in a beneficial way the ECS activation and the lipoperoxidation, taken as indicative of oxidative stress. caryophyllene 50-53 peroxisome proliferator activated receptor alpha Rattus norvegicus 92-102