PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35408995-0	2022	Anti-Inflammatory Effect of Beta-Caryophyllene Mediated by the Involvement of TRPV1, BDNF and trkB in the Rat Cerebral Cortex after Hypoperfusion/Reperfusion.	caryophyllene	28-46	brain-derived neurotrophic factor	Rattus norvegicus	85-89	
35408995-2	2022	Thus in this study, we investigate with immunochemical assays if a single dose of beta-caryophyllene (BCP), administered before the BCCAO/R, can modulate the TRPV1, BDNF, and trkB receptor in the brain cortex; the glial markers GFAP and Iba1 were also examined.	caryophyllene	102-105	brain-derived neurotrophic factor	Rattus norvegicus	165-169	
35408995-6	2022	The BCP treatment caused a decrease of BDNF and an increase of trkB levels in both sham and BCCAO/R conditions while inducing opposite changes in the case of TRPV1, whose levels became higher in BCCAO/R and lower in sham conditions.	caryophyllene	4-7	brain-derived neurotrophic factor	Rattus norvegicus	39-43	
35408995-7	2022	Present results highlight the role of BCP in modulating early events of the cerebral inflammation triggered by the BCCAO/R through the regulation of TRPV1 and the BDNF-trkB system.	caryophyllene	38-41	brain-derived neurotrophic factor	Rattus norvegicus	163-167	
35408995-2	2022	Thus in this study, we investigate with immunochemical assays if a single dose of beta-caryophyllene (BCP), administered before the BCCAO/R, can modulate the TRPV1, BDNF, and trkB receptor in the brain cortex; the glial markers GFAP and Iba1 were also examined.	caryophyllene	82-100	brain-derived neurotrophic factor	Rattus norvegicus	165-169	
30469079-13	2019	Furthermore, BCP-evoked antidepressant and memory improvement are likely mediated only via CB2R, mainly by upregulation of PGC-1alpha and BDNF.	caryophyllene	13-16	brain-derived neurotrophic factor	Rattus norvegicus	138-142	
23414569-6	2013	Western blot analysis demonstrated that TC enhanced phosphorylation of AMP-activated protein kinase (AMPK) and cAMP responsive element-binding protein (CREB), and increased expression of the CREB target gene product, brain-derived neurotrophic factor.	caryophyllene	40-42	brain-derived neurotrophic factor	Rattus norvegicus	217-250	
23414569-9	2013	In rats, post-ischemic treatment with TC decreased cerebral infarct size and edema, and increased phosphorylated CREB and brain-derived neurotrophic factor expression in neurons.	caryophyllene	38-40	brain-derived neurotrophic factor	Rattus norvegicus	122-155