PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27565895-8 2016 BCP pre-treatment prior to the initiation of OGD/R significantly (i) decreased BBB permeability and neuronal apoptosis, (ii) mitigated oxidative stress damage and the release of inflammatory cytokines, (iii) down-regulated Bax expression, metalloproteinase-9 activity and expression, and (iv) up-regulated claudin-5, occludin, ZO-1, growth-associated protein-43 and Bcl-2 expression. caryophyllene 0-3 BCL2 apoptosis regulator Homo sapiens 366-371 29710667-10 2018 Moreover, our results indicated that BCP prevented MPP+-induced apoptosis of SH-SY5Y through inhibiting the up-regulation of cleaved Caspase-3, Bax, and restoring the expression of Bcl-2. caryophyllene 37-40 BCL2 apoptosis regulator Homo sapiens 181-186 34830893-6 2021 BCP treatment reduced cell proliferation through CB2R stimulation; notably, BCP considerably increased the pro-apoptotic protein Bax and decreased the anti-apoptotic molecule Bcl-2. caryophyllene 0-3 BCL2 apoptosis regulator Homo sapiens 175-180