PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16246308-3	2005	Here, using fluorescence resonance energy transfer (FRET) techniques, we show that an elevation of intracellular Ca(2+) concentration by ionomycin increased the FRET efficiency from ECFP (a variant of cyan fluorescent protein)-labeled calmodulin to Venus (a variant of yellow fluorescent protein)-labeled RGS4.	Ionomycin	137-146	calmodulin 1	Homo sapiens	235-245	
9422356-2	1998	Increasing the intracellular Ca2+ concentration with ionomycin also elevates cytosolic CaM.	Ionomycin	53-62	calmodulin 1	Homo sapiens	87-90	
9422356-12	1998	In addition, treatment with ionomycin in the absence of extracellular Ca2+, which releases Ca2+ from intracellular stores, induced an increase in cytosolic CaM (203 +/- 30% of control).	Ionomycin	28-37	calmodulin 1	Homo sapiens	156-159	
2109787-10	1990	The calmodulin inhibitors trifluoperazine and pimozide (30 microM) blocked the cell motility induced by ionomycin while they left the increase of intracellular calcium unaffected.	Ionomycin	104-113	calmodulin 1	Homo sapiens	4-14	
8829112-7	1996	Moreover, the calmodulin inhibitors calmidazolium (10 uM), trifluoperazine (0.1 mM), or W-7 (0.1 mM) significantly inhibited AngII- or ionomycin-activated iCRAC (+106 +/- 38/229 +/- 53, +58 +/- 9/195 +/- 29, +161 +/- 38/180 +/- 40% at 1/10 mM (Ca2+)e, all P < 0.05), but did not affect basal Ca2+ entry, consistent with a direct role of cytoplasmic Ca2+ in the regulation of ion gating.	Ionomycin	135-144	calmodulin 1	Homo sapiens	14-24	
8530476-6	1995	CaM-kinase IV activation was triggered by Ca2+ acting through calmodulin since activation could also be elicited by ionomycin treatment, and CD3-mediated activation was blocked by the calmodulin antagonist calmidazolium.	Ionomycin	116-125	calmodulin 1	Homo sapiens	62-72	
7895032-5	1994	Pretreatment with W-7, a calmodulin antagonist, at concentrations of 10 microM or higher (up to 100 microM) produced a dose-dependent attenuation of ionomycin-induced increase in oxidative metabolism.	Ionomycin	149-158	calmodulin 1	Homo sapiens	25-35	
7895032-6	1994	Results suggest that calmodulin is involved in the ionomycin-induced increase in oxidative metabolism of dissociated cerebellar neurons.	Ionomycin	51-60	calmodulin 1	Homo sapiens	21-31	
2359403-13	1990	The ionophore ionomycin (10 microM) and the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA) (50 nM) were both able to elicit changes in CaM distribution.	Ionomycin	14-23	calmodulin 1	Homo sapiens	145-148	
2359403-14	1990	Ionomycin caused a 64% increase in CaM in the cytosol, with no significant change in membrane CaM.	Ionomycin	0-9	calmodulin 1	Homo sapiens	35-38	
23624269-10	2013	Finally, uric acid attenuated ionomycin-induced increase in the interaction between eNOS and CaM.	Ionomycin	30-39	calmodulin 1	Homo sapiens	93-96	
1692103-4	1990	All the anti-calmodulin agents impaired AVP release to ionomycin, while Ca2+ channel blockade did not.	Ionomycin	55-64	calmodulin 1	Homo sapiens	13-23	
24088894-12	2013	Addition of the Ca(2+) ionophore ionomycin increased the interaction between CaM and NHE1.	Ionomycin	33-42	calmodulin 1	Homo sapiens	77-80