PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24088894-12 2013 Addition of the Ca(2+) ionophore ionomycin increased the interaction between CaM and NHE1. Ionomycin 33-42 calmodulin 1 Homo sapiens 77-80 2359403-13 1990 The ionophore ionomycin (10 microM) and the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA) (50 nM) were both able to elicit changes in CaM distribution. Ionomycin 14-23 calmodulin 1 Homo sapiens 145-148 2359403-14 1990 Ionomycin caused a 64% increase in CaM in the cytosol, with no significant change in membrane CaM. Ionomycin 0-9 calmodulin 1 Homo sapiens 35-38 9422356-2 1998 Increasing the intracellular Ca2+ concentration with ionomycin also elevates cytosolic CaM. Ionomycin 53-62 calmodulin 1 Homo sapiens 87-90 9422356-12 1998 In addition, treatment with ionomycin in the absence of extracellular Ca2+, which releases Ca2+ from intracellular stores, induced an increase in cytosolic CaM (203 +/- 30% of control). Ionomycin 28-37 calmodulin 1 Homo sapiens 156-159 8829112-7 1996 Moreover, the calmodulin inhibitors calmidazolium (10 uM), trifluoperazine (0.1 mM), or W-7 (0.1 mM) significantly inhibited AngII- or ionomycin-activated iCRAC (+106 +/- 38/229 +/- 53, +58 +/- 9/195 +/- 29, +161 +/- 38/180 +/- 40% at 1/10 mM (Ca2+)e, all P < 0.05), but did not affect basal Ca2+ entry, consistent with a direct role of cytoplasmic Ca2+ in the regulation of ion gating. Ionomycin 135-144 calmodulin 1 Homo sapiens 14-24 8530476-6 1995 CaM-kinase IV activation was triggered by Ca2+ acting through calmodulin since activation could also be elicited by ionomycin treatment, and CD3-mediated activation was blocked by the calmodulin antagonist calmidazolium. Ionomycin 116-125 calmodulin 1 Homo sapiens 62-72 7895032-5 1994 Pretreatment with W-7, a calmodulin antagonist, at concentrations of 10 microM or higher (up to 100 microM) produced a dose-dependent attenuation of ionomycin-induced increase in oxidative metabolism. Ionomycin 149-158 calmodulin 1 Homo sapiens 25-35 7895032-6 1994 Results suggest that calmodulin is involved in the ionomycin-induced increase in oxidative metabolism of dissociated cerebellar neurons. Ionomycin 51-60 calmodulin 1 Homo sapiens 21-31 2109787-10 1990 The calmodulin inhibitors trifluoperazine and pimozide (30 microM) blocked the cell motility induced by ionomycin while they left the increase of intracellular calcium unaffected. Ionomycin 104-113 calmodulin 1 Homo sapiens 4-14 1692103-4 1990 All the anti-calmodulin agents impaired AVP release to ionomycin, while Ca2+ channel blockade did not. Ionomycin 55-64 calmodulin 1 Homo sapiens 13-23 23624269-10 2013 Finally, uric acid attenuated ionomycin-induced increase in the interaction between eNOS and CaM. Ionomycin 30-39 calmodulin 1 Homo sapiens 93-96 16246308-3 2005 Here, using fluorescence resonance energy transfer (FRET) techniques, we show that an elevation of intracellular Ca(2+) concentration by ionomycin increased the FRET efficiency from ECFP (a variant of cyan fluorescent protein)-labeled calmodulin to Venus (a variant of yellow fluorescent protein)-labeled RGS4. Ionomycin 137-146 calmodulin 1 Homo sapiens 235-245