PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28634229-10	2017	Ionomycin-induced Ca2+ influx promoted p-Akt, an effect blocked by PDK1, and/or CaMKK2, siRNAs, and by PI3K and/or CaMKK inhibitors.	Ionomycin	0-9	AKT serine/threonine kinase 1	Homo sapiens	41-44	
33023539-5	2020	The expression of Egr2 and FasL, and the phosphorylation of AKT and ERK, after ionomycin and PMA co-stimulation, was detected, while the Ca2+ mobilization stimulated by K+ solution was determined.	Ionomycin	79-88	AKT serine/threonine kinase 1	Homo sapiens	60-63	
29293671-6	2018	Ionomycin, a calcium ionophore, also induced PLSCR1 activation resulting in Akt externalization, suggesting a previously unrecognized biological phenomenon.	Ionomycin	0-9	AKT serine/threonine kinase 1	Homo sapiens	76-79	
11976320-7	2002	Ionomycin and CaMKKc overexpression increases Akt phosphorylation on Thr(308) and enzyme activity.	Ionomycin	0-9	AKT serine/threonine kinase 1	Homo sapiens	46-49	
11976320-9	2002	Furthermore, a dominant negative mutant of Akt abolishes IKKbeta inhibition by CaMKKc and ionomycin, suggesting that Akt acts as a mediator of CaMKK signaling to inhibit IL-1beta-induced IKK activity at an upstream target site.	Ionomycin	90-99	AKT serine/threonine kinase 1	Homo sapiens	43-46	
11976320-9	2002	Furthermore, a dominant negative mutant of Akt abolishes IKKbeta inhibition by CaMKKc and ionomycin, suggesting that Akt acts as a mediator of CaMKK signaling to inhibit IL-1beta-induced IKK activity at an upstream target site.	Ionomycin	90-99	AKT serine/threonine kinase 1	Homo sapiens	117-120	
10362672-4	1999	Akt/PKB activity was stimulated by the Ca2+ ionophore ionomycin, suggesting the possible involvement of Ca2+ in ANG II-stimulated Akt/PKB activation.	Ionomycin	54-63	AKT serine/threonine kinase 1	Homo sapiens	0-3	
10362672-4	1999	Akt/PKB activity was stimulated by the Ca2+ ionophore ionomycin, suggesting the possible involvement of Ca2+ in ANG II-stimulated Akt/PKB activation.	Ionomycin	54-63	AKT serine/threonine kinase 1	Homo sapiens	4-7	
10362672-4	1999	Akt/PKB activity was stimulated by the Ca2+ ionophore ionomycin, suggesting the possible involvement of Ca2+ in ANG II-stimulated Akt/PKB activation.	Ionomycin	54-63	AKT serine/threonine kinase 1	Homo sapiens	130-133	
10362672-4	1999	Akt/PKB activity was stimulated by the Ca2+ ionophore ionomycin, suggesting the possible involvement of Ca2+ in ANG II-stimulated Akt/PKB activation.	Ionomycin	54-63	AKT serine/threonine kinase 1	Homo sapiens	134-137