PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9553058-2 1998 We have identified a distal IL-2 enhancer regulated by the Raf-MEK-ERK signaling pathway, which can be induced by TPA/ionomycin treatment. Ionomycin 118-127 zinc fingers and homeoboxes 2 Homo sapiens 59-62 10373510-13 1999 In the absence of ionomycin, 293T cells expressing wild-type GRF1 contained much higher levels of Ras-GTP than control cells; the increase in Erk activity induced by ionomycin in the GRF1-expressing cells also induced a concomitant increase in Raf kinase activity, but without a further increase in the level Ras-GTP. Ionomycin 166-175 zinc fingers and homeoboxes 2 Homo sapiens 244-247 9553058-7 1998 Furthermore, the JNK/SAPK signaling pathway cooperates with the Raf-MEK-ERK cascade in TPA/ionomycin-induced DSE activity. Ionomycin 91-100 zinc fingers and homeoboxes 2 Homo sapiens 64-67