PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25713079-8	2015	Ionomycin, in the presence of extracellular Ca(2+), elicited a slow, sustained contraction and Pyk2 autophosphorylation, which were blocked by pre-treatment with PF-431396.	Ionomycin	0-9	protein tyrosine kinase 2 beta	Homo sapiens	95-99	
15158121-4	2004	ET-1, PE or the Ca(2+) inophore, ionomycin, stimulated a rapid increase in tyrosine phosphorylation of Pyk2.	Ionomycin	33-42	protein tyrosine kinase 2 beta	Homo sapiens	103-107	
12231407-12	2002	Increasing intracellular calcium with ionomycin caused a decrease in the tyrosine phosphorylation of Pyk2 and the loss of the actin ring in a manner similar to the effect of calcitonin.	Ionomycin	38-47	protein tyrosine kinase 2 beta	Homo sapiens	101-105	
18667434-4	2008	The ionomycin-induced Pyk2 phosphorylation was partially sensitive to AG1478, heparin, or the matrix-metalloproteinase inhibitor BB2116, and the ionomycin-induced EGF receptor phosphorylation was almost completely blocked by these inhibitors of extracellular transactivation.	Ionomycin	4-13	protein tyrosine kinase 2 beta	Homo sapiens	22-26	
18667434-4	2008	The ionomycin-induced Pyk2 phosphorylation was partially sensitive to AG1478, heparin, or the matrix-metalloproteinase inhibitor BB2116, and the ionomycin-induced EGF receptor phosphorylation was almost completely blocked by these inhibitors of extracellular transactivation.	Ionomycin	145-154	protein tyrosine kinase 2 beta	Homo sapiens	22-26	
20688918-4	2010	Ionomycin-stimulated Pyk2 phosphorylation did not require calmodulin activity, because phosphorylation was not inhibited by the calmodulin inhibitor W7, and we detected no Ca(2+)-regulated association between Pyk2 and calmodulin.	Ionomycin	0-9	protein tyrosine kinase 2 beta	Homo sapiens	21-25	
20688918-6	2010	We sought to identify a Ca(2+)-regulated pathway that could trigger Pyk2 phosphorylation in T cells and found that ionomycin stimulated the production of reactive oxygen species and an H(2)O(2) scavenger inhibited ionomycin-induced Pyk2 phosphorylation.	Ionomycin	115-124	protein tyrosine kinase 2 beta	Homo sapiens	68-72	
20688918-6	2010	We sought to identify a Ca(2+)-regulated pathway that could trigger Pyk2 phosphorylation in T cells and found that ionomycin stimulated the production of reactive oxygen species and an H(2)O(2) scavenger inhibited ionomycin-induced Pyk2 phosphorylation.	Ionomycin	115-124	protein tyrosine kinase 2 beta	Homo sapiens	232-236	
20688918-6	2010	We sought to identify a Ca(2+)-regulated pathway that could trigger Pyk2 phosphorylation in T cells and found that ionomycin stimulated the production of reactive oxygen species and an H(2)O(2) scavenger inhibited ionomycin-induced Pyk2 phosphorylation.	Ionomycin	214-223	protein tyrosine kinase 2 beta	Homo sapiens	68-72	
20688918-7	2010	Additionally, H(2)O(2) induced strong Erk activation and ionomycin-stimulated Pyk2 phosphorylation was Erk dependent.	Ionomycin	57-66	protein tyrosine kinase 2 beta	Homo sapiens	78-82