PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1654095-2 1991 The calcium ionophore ionomycin and the tumor promoter thapsigargin stimulated leukotriene production and translocation of 5-lipoxygenase to the membrane. Ionomycin 22-31 arachidonate 5-lipoxygenase Homo sapiens 123-137 1902789-2 1991 Using ionomycin we can show that from the two enzymes involved, phospholipase A2 and 5-lipoxygenase, the first requires a threshold level of about 350-400 nM calcium whereas 5-lipoxygenase shows a linear dependence on calcium and saturates at this concentration. Ionomycin 6-15 arachidonate 5-lipoxygenase Homo sapiens 85-99 1902789-2 1991 Using ionomycin we can show that from the two enzymes involved, phospholipase A2 and 5-lipoxygenase, the first requires a threshold level of about 350-400 nM calcium whereas 5-lipoxygenase shows a linear dependence on calcium and saturates at this concentration. Ionomycin 6-15 arachidonate 5-lipoxygenase Homo sapiens 174-188 1902789-8 1991 In contrast ionomycin-elicited 5-lipoxygenase activity could be stopped at any time shortly after EGTA addition. Ionomycin 12-21 arachidonate 5-lipoxygenase Homo sapiens 31-45