PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23711861-8	2013	Furthermore, the ex vivo production of interleukin (IL)-5 by PBMCs in response to both mite allergen and ionomycin/PMA decreased significantly.	Ionomycin	105-114	interleukin 5	Homo sapiens	39-57	
11517513-4	2001	Interleukin (IL)-5 production by PBMCs stimulated with the combination of phorbol myristate acetate and ionomycin were reduced significantly 6 or 12 weeks after the treatment with supratast tosilate.	Ionomycin	104-113	interleukin 5	Homo sapiens	0-18	
12657248-6	2002	Furthermore, IL-2, IL-4, IL-5, and IFN-gamma secretion by Hut 78 cells or CD3(+) T cells stimulated with PMA plus ionomycin or anti-CD3 antibody plus PMA were inhibited in a concentration-dependent manner by BTPs.	Ionomycin	114-123	interleukin 5	Homo sapiens	25-29	
11961080-5	2002	The IC(50) for IL-5 and IL-13 in TPA/ionomycin-stimulated peripheral blood mononuclear cells (PBMC) is 0.7 +/- 0.1 and 0.5 +/- 0.1 microM, respectively, whereas the IC(50) for IFN-gamma is 2.0 +/- 0.4 microM.	Ionomycin	37-46	interleukin 5	Homo sapiens	15-19	
11745390-7	2001	In addition, we show that in vivo inducible expression of Tax protein in Jurkat T cells stably transfected with Tax further increased ionomycin plus phorbol ester stimulated IL-5 promoter activity.	Ionomycin	134-143	interleukin 5	Homo sapiens	174-178	
9814725-8	1998	Interestingly, in PMA + ionomycin stimulated cultures, the atopic cytokine profile was different with more IL-5 (P = 0.0068) and less IFN-gamma production (P = 0.00046) than the control group.	Ionomycin	24-33	interleukin 5	Homo sapiens	107-111	
11238569-4	2001	Moreover, the NK cells from MS in remission produced much larger amounts of IL-5 than did those from controls after stimulation with phorbol myristate acetate (PMA) and ionomycin.	Ionomycin	169-178	interleukin 5	Homo sapiens	76-80	
9503684-5	1997	Furthermore, the frequency of T cells which produced IL-4, IL-5 and IFN-gamma stimulated with phorbol myristate acetate and ionomycin increased and reduced in parallel with MFI of EG2-positive cells.	Ionomycin	124-133	interleukin 5	Homo sapiens	59-63	
9095665-4	1997	IL-5 production by activated T-lymphocytes which are known to play a major role in chronic GVHD was upregulated when stimulated by PMA + ionomycin.	Ionomycin	137-146	interleukin 5	Homo sapiens	0-4	
9107303-10	1997	After activation with phorbol myristate acetate and ionomycin, the half-life of IL-5 mRNA was 2.6 h in HSB-2 cells and 4.0 h in T cells prepared from human blood.	Ionomycin	52-61	interleukin 5	Homo sapiens	80-84	
7622767-2	1995	To examine the pattern of cytokine production associated with elevated IgE levels, phorbol ester plus ionomycin-stimulated production of interleukin (IL)-4, IL-5, and interferon-gamma (IFN-gamma) by blood mononuclear cells from 16 patients with atopic dermatitis was compared with that of 18 healthy subjects.	Ionomycin	102-111	interleukin 5	Homo sapiens	157-161	
8973627-4	1996	The CD4+CD7- subpopulation was found to secrete significantly higher levels of IL-5 compared with the CD4+CD7- subset upon stimulation with ionomycin/phorbol myristate acetate (PMA) plus anti-CD28 MoAbs.	Ionomycin	140-149	interleukin 5	Homo sapiens	79-83	
7664804-6	1995	The segregation of IL-4 and IL-5 in activated peripheral T cells was found within 72 h of activation upon anti-CD3 or phorbol ester + ionomycin stimulation.	Ionomycin	134-143	interleukin 5	Homo sapiens	28-32	
8625537-9	1996	Similar but transient inhibition of most T-cell products (IL-2, IL-3, IL-4, IL-5, IL-10, TNF-beta and GM-CSF) was noted in the PMA/ionomycin-containing cultures.	Ionomycin	131-140	interleukin 5	Homo sapiens	76-80	
7594459-3	1995	These activated T cells produced IL-2, IL-4, IL-5, and IFN-gamma upon stimulation with PMA and ionomycin.	Ionomycin	95-104	interleukin 5	Homo sapiens	45-49	
7542077-2	1995	Stimuli delivered by the combination of phorbol ester (PMA) and CA2+ ionophore (ionomycin) induced marked IL-5 production by PBMCs obtained from atopic as well as nonatopic asthmatics.	Ionomycin	80-89	interleukin 5	Homo sapiens	106-110	
7512393-1	1994	Upon stimulation with phorbol ester and ionomycin, peripheral blood mononuclear cells (PBMC) of atopic patients with moderate eosinophilia produced significantly higher amounts of IL-5 compared to that of normal subjects.	Ionomycin	40-49	interleukin 5	Homo sapiens	180-184	
7875222-3	1995	Initial stimulation of CD4+ cells with anti-CD3 (or the mitogens PHA or PMA+ionomycin) and anti-CD28 monoclonal antibodies induced IL-4, IL-5 and interferon-gamma (IFN-gamma) production and augmented IL-2 production (6- to 11-fold) compared to cells stimulated with anti-CD3 or mitogen alone.	Ionomycin	76-85	interleukin 5	Homo sapiens	137-141	
7909823-6	1994	Primed cells are enriched in CD45R0hi and CD31- cells, and upon stimulation with PMA+ ionomycin they release significant amounts of IL-2, IFN-gamma, IL-4, IL-5, and IL-10.	Ionomycin	86-95	interleukin 5	Homo sapiens	155-159	
1371491-8	1992	When the cells were stimulated by phorbol ester (phorbol 12-myristate 13-acetate, PMA) plus calcium ionophore (ionomycin), FK506 and CsA inhibited, in a dose-dependent manner, the production of IL-2, IL-4, IL-5, IFN-gamma and TNF-alpha.	Ionomycin	111-120	interleukin 5	Homo sapiens	206-210	
1493921-2	1992	IL-5 expression was stimulated by phytohaemagglutinin (PHA), IL-2, phorbol myristate acetate (PMA) or Ionomycin.	Ionomycin	102-111	interleukin 5	Homo sapiens	0-4	
1493921-5	1992	Dexamethasone at 10(-6) M also profoundly inhibited the IL-5 response to PMA and to IL-2, but the IL-5 response to Ionomycin was not significantly affected.	Ionomycin	115-124	interleukin 5	Homo sapiens	98-102