PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24088894-12	2013	Addition of the Ca(2+) ionophore ionomycin increased the interaction between CaM and NHE1.	Ionomycin	33-42	solute carrier family 9 member A1	Homo sapiens	85-89	
8175807-3	1994	In wild-type transfectants, a short (up to 1 min) incubation with ionomycin induced a significant alkaline shift (approximately 0.2 pH unit) in the intracellular pH (pHi) dependence of the rate of 5-(N-ethyl-N-isopropyl) amiloride-sensitive 22Na+ uptake, without changes in the cell volume and phosphorylation state of NHE1.	Ionomycin	66-75	solute carrier family 9 member A1	Homo sapiens	319-323	
8175807-5	1994	These same mutations abolished the ionomycin-induced NHE1 activation.	Ionomycin	35-44	solute carrier family 9 member A1	Homo sapiens	53-57	
7592862-6	1995	Among stimuli tested (ionomycin, alpha-thrombin, phorbol ester, hyperosmotic stress, and platelet-derived growth factor) that are all known to activate NHE1, only ionomycin and thrombin induced a significant intracellular Ca2+ mobilization and early activation of 22Na+ uptake, implying that Ca2+ is a main regulator of NHE1 in the early phase of the agonist response.	Ionomycin	22-31	solute carrier family 9 member A1	Homo sapiens	152-156	
7592862-6	1995	Among stimuli tested (ionomycin, alpha-thrombin, phorbol ester, hyperosmotic stress, and platelet-derived growth factor) that are all known to activate NHE1, only ionomycin and thrombin induced a significant intracellular Ca2+ mobilization and early activation of 22Na+ uptake, implying that Ca2+ is a main regulator of NHE1 in the early phase of the agonist response.	Ionomycin	163-172	solute carrier family 9 member A1	Homo sapiens	152-156	
7592862-6	1995	Among stimuli tested (ionomycin, alpha-thrombin, phorbol ester, hyperosmotic stress, and platelet-derived growth factor) that are all known to activate NHE1, only ionomycin and thrombin induced a significant intracellular Ca2+ mobilization and early activation of 22Na+ uptake, implying that Ca2+ is a main regulator of NHE1 in the early phase of the agonist response.	Ionomycin	163-172	solute carrier family 9 member A1	Homo sapiens	320-324	
8175807-2	1994	To understand how the intracellular Ca2+ is involved in this activation process, we investigated the effect of Ca2+ ionophore ionomycin on activity of the wild-type or mutant NHE1 expressed in the exchanger-deficient fibroblasts (PS120).	Ionomycin	126-135	solute carrier family 9 member A1	Homo sapiens	175-179