PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9670939-9 1998 The intracellular incorporation of Abs specific for c-Fos and c-Jun family members by scrape loading inhibited the production and intracellular accumulation of IL-2 within 6 h of costimulation with PMA/ionomycin, or costimulation by CD28 and CD3 ligation. Ionomycin 202-211 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 52-57 9507015-10 1998 The focal adhesion dependence of IL-1-induced ERK activation and c-fos expression could be circumvented in cells plated on poly-L-lysine by simultaneous incubation with IL-1 and the calcium ionophore ionomycin. Ionomycin 200-209 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 65-70 9650640-4 1998 We report that c-fos is induced in these cells by both protein kinase C- (PKC-) dependent (phorbol ester, platelet-derived growth factor), and independent (serum, ionomycin) mechanisms. Ionomycin 163-172 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 15-20 9133600-7 1997 The PMA/ionomycin-inducible complex contains NF-ATp/c, Fos and Jun. Ionomycin 8-17 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 55-58 8928840-6 1996 In addition, a selective PTK inhibitor blocked induction of c-fos mRNA by ionomycin, suggesting that Ca(2+)-stimulated PTKs contribute to a signaling pathway regulating immediate early gene expression. Ionomycin 74-83 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 60-65 8485167-4 1993 On the other hand, a calcium ionophore ionomycin elevated both cytosolic Ca2+ and c-fos mRNA but could not antagonize the vacuole formation induced by teleocidin. Ionomycin 39-48 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 82-87 1902229-10 1991 Experiments using phorbol ester (phorbol 12-myristate 13-acetate) in combination with the Ca2+ ionophore ionomycin confirm that activation of protein kinase C induces c-fos and c-jun expression and that a concomitant increase in cytosolic [Ca2+] potentiates the induction of c-fos while repressing that of c-jun. Ionomycin 105-114 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 167-172 1902229-10 1991 Experiments using phorbol ester (phorbol 12-myristate 13-acetate) in combination with the Ca2+ ionophore ionomycin confirm that activation of protein kinase C induces c-fos and c-jun expression and that a concomitant increase in cytosolic [Ca2+] potentiates the induction of c-fos while repressing that of c-jun. Ionomycin 105-114 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 275-280 2119237-9 1990 Interleukin-1 beta (IL-1 beta) and basic fibroblast growth factor (bFGF) stimulation of c-fos mRNA level were not inhibited by quin2; on the contrary, ionomycin effect was blocked by this agent. Ionomycin 151-160 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 88-93 3495445-5 1987 Stimulation of B lymphocytes with TPA plus ionomycin resulted in increased magnitude and a shift in the kinetics of c-fos and c-myc expression compared with either agent used alone. Ionomycin 43-52 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 116-121 7994752-2 1994 Data presented here demonstrate that stimulation of mIgM-bearing cells with either anti-IgM or the combination of PDB plus ionomycin generated comparable levels of c-fos RNA. Ionomycin 123-132 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 164-169 7962120-5 1994 Phorbol 12-myristate 13-acetate (PMA), an activator of protein kinase C (PKC), induced an intense expression of the c-fos gene, while 4 alpha-phorbol 12,13-didecanoate (4 alpha PDD), incapable of activating PKC, and calcium ionophores (A23187 and ionomycin) did not. Ionomycin 247-256 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 116-121 7693480-5 1993 c-fos and 1R20 were also the only ERG inducible in response to IL-4 stimulation and whilst ionomycin induced only c-fos, dibutyryl cyclic adenosine monophosphate stimulation led to induction of both c-fos and 1R20. Ionomycin 91-100 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 114-119 7693480-5 1993 c-fos and 1R20 were also the only ERG inducible in response to IL-4 stimulation and whilst ionomycin induced only c-fos, dibutyryl cyclic adenosine monophosphate stimulation led to induction of both c-fos and 1R20. Ionomycin 91-100 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 114-119 3141428-11 1988 The calcium ionophores, A23187 and ionomycin, previously shown to induce an increase in c-myc and c-fos mRNA levels in fibroblasts, induced a marked increase in the synthesis of a nuclear protein at 80 kD/pI-5 but failed to induce an increase in the synthesis of numatrin indicating that an increase in intracellular Ca++ level is not sufficient for induction of the synthesis of numatrin. Ionomycin 35-44 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 98-103 30777021-6 2019 Electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation-quantitative polymerase chain reaction (ChIP-qPCR) assays showed that the risk allele of the variant was bound to activator protein 1 transcription factors (c-Fos and c-Jun) with a significantly reduced affinity and associated with decreased mRNA expression of FGF7 in fibroblast cells at both resting and PMA/Ionomycin-stimulated conditions. Ionomycin 388-397 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 235-240 20432446-3 2010 Here we report the effects of low-concentration (1 microg/ml) heparin on activation of several kinases and subsequent induction of the c-fos gene in mesangial cells in response to the calcium ionophore, ionomycin, in the absence of serum factors. Ionomycin 203-212 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 135-140