PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6088030-1 1984 Using the all-valence electron, semiempirical molecular orbital method, MNDO, properties have been identified and calculated for eight chloroethanes which can serve as indicators of their extent of transformation to alcohols by cytochrome P450 and the subsequent formation of aldehydes by loss of HCl from these alcohols. Ethyl Chloride 135-148 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 228-243 6088030-5 1984 The molecular properties identified in this study as indicators of rank order or carcinogenic activity of the parent chloroethanes are consistent with the importance of cytochrome P450 in transforming halohydrocarbons to active carcinogens and of acylchlorides and chloroaldehydes as the active form. Ethyl Chloride 117-130 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 169-184 7285278-0 1981 Chloroethanes : their metabolism by hepatic cytochrome P-450 in vitro. Ethyl Chloride 0-13 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 44-60