PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1310515-0	1992	Comparative effects of tetrandrine and berbamine on production of the inflammatory cytokines interleukin-1 and tumor necrosis factor.	tetrandrine	23-34	interleukin 1 alpha	Homo sapiens	93-132	
2539275-0	1989	Suppression of human monocyte interleukin 1 production by the plant alkaloid tetrandrine.	tetrandrine	77-88	interleukin 1 alpha	Homo sapiens	30-43	
2539275-4	1989	Tetrandrine may be of value in the treatment of chronic inflammatory diseases where IL-1 has a major role as an inflammatory mediator.	tetrandrine	0-11	interleukin 1 alpha	Homo sapiens	84-88	
33140671-14	2022	Additionally, TET promoted macrophage transformation from M1 to M2 in osteoporotic and inhibited the production of IL-1beta, TNF-alpha, and IL-6.	tetrandrine	14-17	interleukin 1 alpha	Homo sapiens	115-123	
1310515-1	1992	Tetrandrine and berbamine are bisbenzylisoquinoline compounds which differ from each other in a minor way in terms of chemical structure, yet tetrandrine is 6-18 times more potent than berbamine in terms of inhibitory effects on production of interleukin-1 and tumor necrosis factor (TNF alpha) by monocytes and macrophages, and TNF beta production by lymphocytes.	tetrandrine	0-11	interleukin 1 alpha	Homo sapiens	243-282	
1310515-1	1992	Tetrandrine and berbamine are bisbenzylisoquinoline compounds which differ from each other in a minor way in terms of chemical structure, yet tetrandrine is 6-18 times more potent than berbamine in terms of inhibitory effects on production of interleukin-1 and tumor necrosis factor (TNF alpha) by monocytes and macrophages, and TNF beta production by lymphocytes.	tetrandrine	142-153	interleukin 1 alpha	Homo sapiens	243-282