PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18348409-5	2007	Western blotting was employed to detect cyclin B 1 and Cdc2 proteins in extracts from irradiated or non-irradiated cells of MCF-7/ADR, HT-29 and MCF-7 treated with tetrandrine at various concentrations.	tetrandrine	164-175	cyclin B1	Homo sapiens	40-50	
21797675-5	2011	Further, expression of cyclin B1 protein increased after addition of tetrandrine when compared with radiation only.	tetrandrine	69-80	cyclin B1	Homo sapiens	23-32	
17989878-6	2007	The accumulation of cyclinB1 protein and the suppression of Cdc2 tyrosine-15 and Cdc25C serine-216 phosphorylation were detected in irradiated cells treated with tetrandrine using Western blot analysis.	tetrandrine	162-173	cyclin B1	Homo sapiens	20-28	
31255635-8	2019	Cell cycle arrest at S phase accompanied by increase in the amounts of cyclin A2 and cyclin B1, and decrease in cylcin D1 amount in cells treated with TET or CEP will be another possible mechanism.	tetrandrine	151-154	cyclin B1	Homo sapiens	85-94	
29285984-0	2018	Tetrandrine enhances radiosensitivity through the CDC25C/CDK1/cyclin B1 pathway in nasopharyngeal carcinoma cells.	tetrandrine	0-11	cyclin B1	Homo sapiens	62-71	
29285984-11	2018	Combined treatment with the maximum non-cytotoxic dose of tetrandrine and irradiation caused suppression of the phosphorylation of CDK1 and CDC25C and increase in the expression of cyclin B1.	tetrandrine	58-69	cyclin B1	Homo sapiens	181-190	
29285984-13	2018	Our results suggest that the maximum non-cytotoxic dose of tetrandrine can enhance the radiosensitivity of CNE1 and CNE2 cells and that the underlying mechanism could be associated with abrogation of radiation-induced G2/M arrest via activation of the CDC25C/CDK1/Cyclin B1 pathway.	tetrandrine	59-70	cyclin B1	Homo sapiens	264-273