PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21169404-5 2011 Mthfr deficiency was also associated with increased ROS production and reduced nitric oxide (NO) generation in Mthfr(+/-) EPCs. Nitric Oxide 79-91 methylenetetrahydrofolate reductase Mus musculus 0-5 12829522-11 2003 CONCLUSIONS: Mthfr+/- mice show endothelial dysfunction of mesenteric vessels probably attributable to a reduced nitric oxide bioavailability caused by oxidative excess due to uncoupling of nitric oxide synthase without vascular structural alterations. Nitric Oxide 113-125 methylenetetrahydrofolate reductase Mus musculus 13-18