PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31446221-2	2019	The KL gene plays roles in endothelial nitric oxide production, angiogenesis, antioxidant enzyme production and protecting against endothelial dysfunction, all of which may be associated with preeclampsia (PE).	Nitric Oxide	39-51	klotho	Homo sapiens	4-6	
17709902-5	2007	Furthermore, Klotho-CM increased nitric oxide production, which also contributed to the up-regulation of Mn-SOD.	Nitric Oxide	33-45	klotho	Homo sapiens	13-19	
30576222-5	2019	Klotho protein also reduced the rate of apoptosis of cells and improved the function of vascular endothelial cells (increased nitric oxide secretion).	Nitric Oxide	126-138	klotho	Homo sapiens	0-6	
27448998-3	2016	In vitro experiments were performed to assess the effects of FGF23 (10 ng/mL) in relation to its co-receptor Klotho on nitric oxide (NO) synthesis and reactive oxygen species (ROS) formation and detoxification in human coronary artery endothelial cells (HCAEC).	Nitric Oxide	119-131	klotho	Homo sapiens	109-115	
21543107-1	2011	INTRODUCTION: Despite experimental evidences of the influence of the aging suppressor gene Klotho, on the modulation of endothelial nitric oxide synthase (eNOS) activity and nitric oxide (NO) production, the contribution of its variants to the phenotypic variance of plasma nitrite and nitrate (NO(x)) has not been addressed to date.	Nitric Oxide	132-144	klotho	Homo sapiens	91-97	
34125262-3	2021	The KL gene and its encoded proteins are implicated in important biological pathways, which affect the disease"s pathophysiology, such as expression of adhesion molecules VCAM-1 and ICAM-1, oxidative stress, and nitric oxide biology.	Nitric Oxide	212-224	klotho	Homo sapiens	4-6