PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28774789-9	2018	Furthermore, compared to rAAV-Vector, rAAV-Cbs injection reduced the aberrant accumulation of nitric oxide and 3-nitrotyrosine (an indicator of protein nitration) in the striatum of MPTP-treated mice.	Nitric Oxide	94-106	cystathionine beta-synthase	Mus musculus	43-46	
28774789-12	2018	Moreover, glial CBS overexpression offered protection to midbrain dopaminergic neurons through repressing nitric oxide overproduction in both glial and neuronal cells induced by MPP+.	Nitric Oxide	106-118	cystathionine beta-synthase	Mus musculus	16-19	
19085910-3	2009	Studies using recombinant CBS indicated that CO binds to the prosthetic heme, stabilizing 6-coordinated CO-Fe(II)-histidine complex to block the activity, whereas nitric oxide (NO) forms 5-coordinated structure without inhibiting it.	Nitric Oxide	163-175	cystathionine beta-synthase	Mus musculus	26-29	
28665886-10	2017	In addition, CBS+/- mice showed increased oxidative stress, inflammation and decreased nitric oxide.	Nitric Oxide	87-99	cystathionine beta-synthase	Mus musculus	13-16	
10953023-9	2000	Hence, mild hyperhomocysteinemia due to reduced CBS expression impairs endothelium-dependent vasodilation, likely due to impaired nitric oxide bioactivity, and increased oxidative stress apparently contributes to inactivating nitric oxide in chronic, mild hyperhomocysteinemia.	Nitric Oxide	130-142	cystathionine beta-synthase	Mus musculus	48-51