PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29844863-3 2018 We have designed and tested both in vitro and in vivo, a monoamine oxidase B (MAOB) specific prodrug, PAM-OBG, that is converted by glioma MAOB into the MGMT inhibitor O6-benzylguanine (O6BG) and the DNA crosslinking agent acrolein. O(6)-benzylguanine 168-184 monoamine oxidase B Homo sapiens 57-76 29844863-3 2018 We have designed and tested both in vitro and in vivo, a monoamine oxidase B (MAOB) specific prodrug, PAM-OBG, that is converted by glioma MAOB into the MGMT inhibitor O6-benzylguanine (O6BG) and the DNA crosslinking agent acrolein. O(6)-benzylguanine 168-184 monoamine oxidase B Homo sapiens 78-82 29844863-3 2018 We have designed and tested both in vitro and in vivo, a monoamine oxidase B (MAOB) specific prodrug, PAM-OBG, that is converted by glioma MAOB into the MGMT inhibitor O6-benzylguanine (O6BG) and the DNA crosslinking agent acrolein. O(6)-benzylguanine 168-184 monoamine oxidase B Homo sapiens 139-143 29844863-3 2018 We have designed and tested both in vitro and in vivo, a monoamine oxidase B (MAOB) specific prodrug, PAM-OBG, that is converted by glioma MAOB into the MGMT inhibitor O6-benzylguanine (O6BG) and the DNA crosslinking agent acrolein. O(6)-benzylguanine 186-190 monoamine oxidase B Homo sapiens 57-76 29844863-3 2018 We have designed and tested both in vitro and in vivo, a monoamine oxidase B (MAOB) specific prodrug, PAM-OBG, that is converted by glioma MAOB into the MGMT inhibitor O6-benzylguanine (O6BG) and the DNA crosslinking agent acrolein. O(6)-benzylguanine 186-190 monoamine oxidase B Homo sapiens 78-82 29844863-3 2018 We have designed and tested both in vitro and in vivo, a monoamine oxidase B (MAOB) specific prodrug, PAM-OBG, that is converted by glioma MAOB into the MGMT inhibitor O6-benzylguanine (O6BG) and the DNA crosslinking agent acrolein. O(6)-benzylguanine 186-190 monoamine oxidase B Homo sapiens 139-143