PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31712163-0	2020	Resveratrol induces depletion of TRAF6 and suppresses prostate cancer cell proliferation and migration.	Resveratrol	0-11	LOC222344	Homo sapiens	33-38	
31712163-3	2020	Herein, we investigated the effect and mechanism of resveratrol function in PCa cell proliferation and migration and reported that TNF-receptor associated factor 6 (TRAF6), an unconventional E3 ligase, is a key mediator of resveratrol function to inhibit PCa cell growth and proliferation and targeted for lysosomal degradation by resveratrol.	Resveratrol	52-63	LOC222344	Homo sapiens	131-163	
31712163-3	2020	Herein, we investigated the effect and mechanism of resveratrol function in PCa cell proliferation and migration and reported that TNF-receptor associated factor 6 (TRAF6), an unconventional E3 ligase, is a key mediator of resveratrol function to inhibit PCa cell growth and proliferation and targeted for lysosomal degradation by resveratrol.	Resveratrol	52-63	LOC222344	Homo sapiens	165-170	
31712163-3	2020	Herein, we investigated the effect and mechanism of resveratrol function in PCa cell proliferation and migration and reported that TNF-receptor associated factor 6 (TRAF6), an unconventional E3 ligase, is a key mediator of resveratrol function to inhibit PCa cell growth and proliferation and targeted for lysosomal degradation by resveratrol.	Resveratrol	223-234	LOC222344	Homo sapiens	131-163	
31712163-3	2020	Herein, we investigated the effect and mechanism of resveratrol function in PCa cell proliferation and migration and reported that TNF-receptor associated factor 6 (TRAF6), an unconventional E3 ligase, is a key mediator of resveratrol function to inhibit PCa cell growth and proliferation and targeted for lysosomal degradation by resveratrol.	Resveratrol	223-234	LOC222344	Homo sapiens	165-170	
31712163-3	2020	Herein, we investigated the effect and mechanism of resveratrol function in PCa cell proliferation and migration and reported that TNF-receptor associated factor 6 (TRAF6), an unconventional E3 ligase, is a key mediator of resveratrol function to inhibit PCa cell growth and proliferation and targeted for lysosomal degradation by resveratrol.	Resveratrol	223-234	LOC222344	Homo sapiens	131-163	
31712163-3	2020	Herein, we investigated the effect and mechanism of resveratrol function in PCa cell proliferation and migration and reported that TNF-receptor associated factor 6 (TRAF6), an unconventional E3 ligase, is a key mediator of resveratrol function to inhibit PCa cell growth and proliferation and targeted for lysosomal degradation by resveratrol.	Resveratrol	223-234	LOC222344	Homo sapiens	165-170	
31712163-5	2020	Resveratrol (50 muM) mediated the degradation of TRAF6 which in turn facilitated repression of the NF-kappaB pathway.	Resveratrol	0-11	LOC222344	Homo sapiens	49-54	
31712163-6	2020	Also, wound healing and transwell migration assays and level of EMT-related proteins showed that resveratrol used TRAF6, at least in part to inhibit cell migration.	Resveratrol	97-108	LOC222344	Homo sapiens	114-119	
31712163-9	2020	Our exploration exhibited that resveratrol may inhibit EMT through the TRAF6/NF-kappaB/SLUG axis.	Resveratrol	31-42	LOC222344	Homo sapiens	71-76	
31712163-10	2020	Altogether, this study represents that TRAF6 acts as an intermediary of resveratrol action to suppress PCa cell proliferation and migration, and concerns future attention to obtain as a therapeutic target for the treatment of PCa.	Resveratrol	72-83	LOC222344	Homo sapiens	39-44