PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15063831-0 2004 Inhibitory effects of Polygonum cuspidatum water extract (PCWE) and its component resveratrol [correction of rasveratrol] on acyl-coenzyme A-cholesterol acyltransferase activity for cholesteryl ester synthesis in HepG2 cells. Resveratrol 82-93 carboxylesterase 1 Homo sapiens 125-168 15063831-5 2004 Among the main active chemicals of P. cuspidatum, resveratrol, a kind of flavonoid, decreased ACAT activity in a dose-dependent manner from the level of 10(-3) M. Theses results strongly suggest that PCWE reduces the cholesteryl ester formation in human hepatocytes by inhibiting ACAT. Resveratrol 50-61 carboxylesterase 1 Homo sapiens 94-98 15063831-5 2004 Among the main active chemicals of P. cuspidatum, resveratrol, a kind of flavonoid, decreased ACAT activity in a dose-dependent manner from the level of 10(-3) M. Theses results strongly suggest that PCWE reduces the cholesteryl ester formation in human hepatocytes by inhibiting ACAT. Resveratrol 50-61 carboxylesterase 1 Homo sapiens 280-284