PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22095529-5	2012	Finally, we assayed the ability of RSV in modulating the expression of target proteins involved in DNA damage signalling, namely ATR, ATM, Chk1, Chk2 and gammaH2AX.	Resveratrol	35-38	checkpoint kinase 2	Homo sapiens	145-149	
28950914-9	2017	CONCLUSIONS: Our results provide in vitro evidence that RSV produces anti-tumor effect by activating DDR pathway in an ATM/Chk2/p53 dependent manner.	Resveratrol	56-59	checkpoint kinase 2	Homo sapiens	123-127	
22415970-8	2012	The treatment with RSV or MEL increased the levels of p-Chk2.	Resveratrol	19-22	checkpoint kinase 2	Homo sapiens	56-60	
27109601-9	2016	However, resveratrol displayed synergism when combined with metformin as shown by the downregulation of p53/gammaH2AX/p-chk2.	Resveratrol	9-20	checkpoint kinase 2	Homo sapiens	120-124	
22095529-7	2012	Moreover, we show that RSV poisons TOPOIIalpha so inducing DNA damage; ATM, Chk2 and gammaH2AX are involved in the DNA damage signalling after RSV treatment.	Resveratrol	143-146	checkpoint kinase 2	Homo sapiens	76-80	
18454317-7	2008	In melanoma cells, resveratrol inhibits STAT3 and NF-kappaB-dependent transcription, culminating in suppression of cFLIP and Bcl-xL expression, while activating the MAPK- and the ATM-Chk2-p53 pathways.	Resveratrol	19-30	checkpoint kinase 2	Homo sapiens	183-187