PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30241348-3 2018 Pregnenolone, progesterone, 17-OH-pregnenolone, and 17-OH-progesterone increased C21 steroid (5-pregnan-3,20-dione, 5-pregnan-3,17-diol-20-one, 5-pregnan-3-ol-20-one) formation in the backdoor pathway, and demonstrated a trend of stimulating dihydroepiandrosterone or its precursors in the backdoor pathway in LNCaP and 22Rv1 cells. Pregnenolone 0-12 TBL1X/Y related 1 Homo sapiens 81-84 8721049-4 1996 Pregnenolone, a source of C21 steroids, gradually increased during pregnancy. Pregnenolone 0-12 TBL1X/Y related 1 Homo sapiens 26-29 29360536-0 2018 Synthesis and cytotoxic effect of pregnenolone derivatives with one or two alpha,beta-unsaturated carbonyls and an ester moiety at C-21 or C-3. Pregnenolone 34-46 TBL1X/Y related 1 Homo sapiens 131-135 29360536-1 2018 Four series of pregnenolone derivatives having one or two alpha,beta-unsaturated carbonyls and an ester moiety at C-21 or C-3 were synthetized to compare their cytotoxicity effect. Pregnenolone 15-27 TBL1X/Y related 1 Homo sapiens 114-118