PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24306501-3	1994	The sensitivities of PEP carboxylase to the allosteric effectors malate and glucose-6-phosphate were markedly different between C3 and C4 species.	malic acid	65-71	phosphoenolpyruvate carboxylase 2	Zea mays	21-24	
16664876-2	1986	In addition, sensitivity to effectors of PEP carboxylase activity was significantly altered; e.g. malate inhibition was reduced and glucose-6-phosphate activation was increased.	malic acid	98-104	phosphoenolpyruvate carboxylase 2	Zea mays	41-44	
2334435-8	1990	It thus appears that the quaternary structure (oligomeric state) of maize PEP carboxylase can be regulated by the naturally occurring effector molecules Mg-PEP and malate which in turn can control the enzyme"s activity.	malic acid	164-170	phosphoenolpyruvate carboxylase 2	Zea mays	74-77	
16667297-1	1990	Malate has been noted to be a ;mixed" inhibitor of phosphoenolpyruvate (PEP) carboxylase.	malic acid	0-6	phosphoenolpyruvate carboxylase 2	Zea mays	72-75	
16667297-5	1990	The ability of high concentrations of PEP to convert PEPC from a form readily inhibited by malate to one resistant to malate inhibition has been previously demonstrated and we attribute the cooperativity shown at pH 8 to this response to high levels of PEP.	malic acid	91-97	phosphoenolpyruvate carboxylase 2	Zea mays	38-41	
16667297-5	1990	The ability of high concentrations of PEP to convert PEPC from a form readily inhibited by malate to one resistant to malate inhibition has been previously demonstrated and we attribute the cooperativity shown at pH 8 to this response to high levels of PEP.	malic acid	91-97	phosphoenolpyruvate carboxylase 2	Zea mays	53-56	
16667297-5	1990	The ability of high concentrations of PEP to convert PEPC from a form readily inhibited by malate to one resistant to malate inhibition has been previously demonstrated and we attribute the cooperativity shown at pH 8 to this response to high levels of PEP.	malic acid	118-124	phosphoenolpyruvate carboxylase 2	Zea mays	38-41	
16667297-5	1990	The ability of high concentrations of PEP to convert PEPC from a form readily inhibited by malate to one resistant to malate inhibition has been previously demonstrated and we attribute the cooperativity shown at pH 8 to this response to high levels of PEP.	malic acid	118-124	phosphoenolpyruvate carboxylase 2	Zea mays	53-56	
2122805-5	1990	When the enzyme is incubated at pH 7 with 5 mM malate (a treatment known to cause dimerization) subsequent assay at saturating levels of MgPEP completely restores activity while assay at less than Km MgPEP produces greater than 99% inhibition of the same sample, showing that high PEP concentration has reconverted the PEPC to the malate-resistant tetramer.	malic acid	47-53	phosphoenolpyruvate carboxylase 2	Zea mays	139-142	
2122805-5	1990	When the enzyme is incubated at pH 7 with 5 mM malate (a treatment known to cause dimerization) subsequent assay at saturating levels of MgPEP completely restores activity while assay at less than Km MgPEP produces greater than 99% inhibition of the same sample, showing that high PEP concentration has reconverted the PEPC to the malate-resistant tetramer.	malic acid	331-337	phosphoenolpyruvate carboxylase 2	Zea mays	139-142	
16665209-8	1987	Although photosynthetically inactive pools of malate, asparate, and alanine could mask real changes in levels of the photosynthetically active pools of these compounds, the apparent levels of these compounds and the total amount of intermediates in the C(4) cycle (malate, aspartate, pyruvate, PEP, and alanine) increased with increasing Ci.	malic acid	46-52	phosphoenolpyruvate carboxylase 2	Zea mays	294-297	
24414104-6	1978	The pH sensitivity of PEP carboxylase is such that its activity, and thus the rate of malate synthesis, may be enhanced by an increase in cytoplasmic pH accompanying FC-induced H(+) excretion.	malic acid	86-92	phosphoenolpyruvate carboxylase 2	Zea mays	22-25	
24414104-1	1978	The phytotoxin fusicoccin (FC) causes rapid synthesis of malate in coleoptile tissues, presumably via phosphoenolpyruvate (PEP) carboxylase coupled with malate dehydrogenase.	malic acid	57-63	phosphoenolpyruvate carboxylase 2	Zea mays	123-126	
33016576-6	2021	Flux from malate via pyruvate to PEP remained low, commensurate with the low NADP-malic enzyme activity observed in the transgenic lines.	malic acid	10-16	phosphoenolpyruvate carboxylase 2	Zea mays	33-36