PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15657055-0	2005	A five-coordinate metal center in Co(II)-substituted VanX.	vanx	53-57	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	34-40	
17017774-0	2006	Probing the reaction mechanism of the D-ala-D-ala dipeptidase, VanX, by using stopped-flow kinetic and rapid-freeze quench EPR studies on the Co(II)-substituted enzyme.	vanx	63-67	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	142-148	
17017774-1	2006	In an effort to probe the reaction mechanism of VanX, the d-ala-d-ala dipeptidase required for high-level vancomycin resistance in bacteria, stopped-flow kinetic and rapid-freeze quench EPR studies were conducted on the Co(II)-substituted enzyme when reacted with d-ala-d-ala.	vanx	48-52	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	220-226	
17017774-2	2006	The intensity of the Co(II) ligand field band at 550 nm decreased (epsilon550 = 140 to 18 M-1 cm-1) when VanX was reacted with substrate, suggesting that the coordination number of the metal increases from 5 to 6 upon substrate binding.	vanx	105-109	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	21-27	
15657055-5	2005	Single scattering fits of EXAFS data indicate that the metal ions in both native Zn(II)-containing and Co(II)-substituted VanX have the same coordination number and that the metal ions are coordinated by 5 nitrogen/oxygen ligands at approximately 2.0 angstroms.	vanx	122-126	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	103-109	
15657055-6	2005	These data demonstrate that Co(II) (and Zn(II) from EXAFS studies) is five-coordinate in VanX in contrast to previous crystallographic studies (Bussiere, D. E., Pratt, S. D., Katz, L., Severin, J. M., Holzman, T., and Park, C. H. (1998) Mol.	vanx	89-93	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	28-34	
15657055-8	2005	These spectroscopic studies also demonstrate that the metal ion in Co(II)-substituted VanX when complexed with a phosphinate analog of substrate D-Ala-D-Ala is also five-coordinate.	vanx	86-90	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	67-73