PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9292787-0 1997 Quercetin, a bioflavonoid, inhibits the induction of interleukin 8 and monocyte chemoattractant protein-1 expression by tumor necrosis factor-alpha in cultured human synovial cells. Flavonoids 13-25 C-C motif chemokine ligand 2 Homo sapiens 71-105 32923824-0 2020 Elucidating the Molecular Interactions of Chemokine CCL2 Orthologs with Flavonoid Baicalin. Flavonoids 72-81 C-C motif chemokine ligand 2 Homo sapiens 52-56 27770720-4 2016 Their inhibitory effects on LPS-induced inflammatory responses correlated with the intensities of these flavonoids to suppress the LPS-induced activation of nuclear factor kappaB (NF-kappaB), an essential transcription factor for the mRNA expression of iNOS, TNFalpha, and CCL2. Flavonoids 104-114 C-C motif chemokine ligand 2 Homo sapiens 273-277 28443720-9 2017 The induction of the expression of MMP-3 and the downregulation of MCP-1 might result in an antiplatelet activity that was not observed for the micronized purified flavonoid fraction. Flavonoids 164-173 C-C motif chemokine ligand 2 Homo sapiens 67-72 27770720-3 2016 Five types of flavonoids: isoliquiritigenin, chrysin, 3",4"-dihydroxy-4-methoxydalbergione, 4-methoxydalbergion, and cearoin, markedly inhibited inflammatory responses including LPS-induced NO production by suppressing the expression of iNOS mRNA and LPS-induced mRNA expression of TNFalpha and CCL2. Flavonoids 14-24 C-C motif chemokine ligand 2 Homo sapiens 295-299 20309792-9 2010 Molecular docking studies showed that the complementarity of prenylated flavonoids with the hydrophobic MD-2 pocket (indicating goodness of fit) directly predicted their relative ability to inhibit MCP-1 and IL-6 production. Flavonoids 72-82 C-C motif chemokine ligand 2 Homo sapiens 198-203 17320090-8 2007 Compared to placebo (ANOVA and Tukey"s test), flavonoids significantly reduced serum 8-isoprostans (p<0.000) and Ox-LDL levels (p<0.000) (by 38 and 29%, respectively), as well as hsCRP (p<0.007) and MCP-1 (p<0.001) levels (by 23 and 29%, respectively). Flavonoids 46-56 C-C motif chemokine ligand 2 Homo sapiens 208-213