PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35088951-0	2022	Anti-adipogenic effect of the flavonoids through the activation of AMPK in palmitate (PA)-treated HepG2 cells.	Flavonoids	30-40	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	67-71	
35088951-7	2022	The potential interaction between the flavonoids and the gamma-subunit of AMPK was investigated by molecular docking analysis.	Flavonoids	38-48	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	74-78	
35088951-10	2022	The flavonoids increased the AMPK, ACC, and GSK3beta phosphorylation levels and decreased the SREBP-2 and HMGCR expression levels in PA-treated HepG2 cells.	Flavonoids	4-14	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	29-33	
35088951-11	2022	Molecular docking analysis showed that the flavonoids bind to the CBS domains in the regulatory gamma-subunit of AMPK with high binding affinities and could serve as potential AMPK activators.	Flavonoids	43-53	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	113-117	
35088951-11	2022	Molecular docking analysis showed that the flavonoids bind to the CBS domains in the regulatory gamma-subunit of AMPK with high binding affinities and could serve as potential AMPK activators.	Flavonoids	43-53	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	176-180	
35088951-12	2022	CONCLUSION: The overall results suggest that the anti-adipogenic effect of flavonoids on PA-treated HepG2 cells results from the activation of AMPK by flavonoids.	Flavonoids	75-85	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	143-147	
35088951-12	2022	CONCLUSION: The overall results suggest that the anti-adipogenic effect of flavonoids on PA-treated HepG2 cells results from the activation of AMPK by flavonoids.	Flavonoids	151-161	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	143-147	
31093947-3	2019	The main goal of this study was to evaluate the effect of hesperetin, a citrus polyphenolic flavonoid, on SIRT1 and AMP-activated kinase (AMPK).	Flavonoids	92-101	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	116-136	
31093947-3	2019	The main goal of this study was to evaluate the effect of hesperetin, a citrus polyphenolic flavonoid, on SIRT1 and AMP-activated kinase (AMPK).	Flavonoids	92-101	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	138-142	
30304866-9	2018	The complex paradigm will be discussed within the context of if/how dietary components, nutrients including fatty acids and non-nutrient food components, such as resveratrol, berberine, curcumin and the flavonoid genistein, modulate AMPK dependent processes relating to inflammation and metabolism.	Flavonoids	203-212	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	233-237	
25446924-8	2014	Co-treatment with AMPK inhibitor compound C diminished the beneficial effects of these flavonoids, suggesting the involvement of AMPK.	Flavonoids	87-97	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	18-22	
25446924-8	2014	Co-treatment with AMPK inhibitor compound C diminished the beneficial effects of these flavonoids, suggesting the involvement of AMPK.	Flavonoids	87-97	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	129-133	
34854271-8	2021	Both flavonoids increased glucose uptake by promoting the phosphorylation of AMPK at Thr172 and increased the phosphorylation of GSK3beta.	Flavonoids	5-15	protein kinase AMP-activated non-catalytic subunit beta 1	Homo sapiens	77-81