PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24568186-3 2014 In the present work, we investigated the effects of HO-1 on the expression of p53 induced by 15-deoxy-Delta(12,14)-prostaglandin J2 (15d-PGJ2) in human breast cancer (MCF-7) cells. 9-deoxy-delta-9-prostaglandin D2 115-131 tumor protein p53 Homo sapiens 78-81 14704122-3 2004 RESULTS: The 15d-PGJ2 induced apoptosis in ECV304 endothelial cells in a dose-dependent manner (the percentage of apoptosis was enhanced from 10.0 %+/-1.3 % to 32.8 %+/-1.6 %), which was accompanied by inhibition of NF-?B and AP-1 DNA binding activity, down-regulation of c-myc, upregulation of Gadd45 and p53, and activation of p38 kinase. 9-deoxy-delta-9-prostaglandin D2 17-21 tumor protein p53 Homo sapiens 306-309 9792828-0 1998 p53-Independent activation of the gadd45 promoter by Delta12-prostaglandin J2. 9-deoxy-delta-9-prostaglandin D2 61-77 tumor protein p53 Homo sapiens 0-3 14636064-3 2003 In the study presented here, we investigated the molecular mechanisms involved in the 15d-PGJ(2)-induced accumulation of p53. 9-deoxy-delta-9-prostaglandin D2 90-96 tumor protein p53 Homo sapiens 121-124 26801686-3 2016 Therefore, the present study aimed to elucidate the impact of 15-deoxy-Delta(12,14)-PGJ2 (15d-PGJ2, a stable PGD2 degradation product) on cell death/cell survival pathways in p53-deficient MG-63 OS cells. 9-deoxy-delta-9-prostaglandin D2 83-88 tumor protein p53 Homo sapiens 175-178