PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25122757-7 2014 Unlike other AlkB family members whose substrates are DNA or RNA, ALKBH7 is devoid of the "nucleotide recognition lid" which is essential for binding nucleobases, and thus exhibits a solvent-exposed active site; two loops between beta-strands beta6 and beta7 and between beta9 and beta10 create a special outer wall of the minor beta-sheet of the double-stranded beta-helix and form a negatively charged groove. nucleobases 150-161 alkB homolog 7 Homo sapiens 66-72