PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24109558-6 2013 Our data indicate that harmine exhibits a pronounced cytotoxicity and induces an anti-proliferation state in MCF-7 cells which is accompanied by a significant inhibition of telomerase activity and an induction of an accelerated senescence phenotype by over-expressing elements of the p53/p21 pathway. Harmine 23-30 tumor protein p53 Homo sapiens 284-287 22558087-0 2012 JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21. Harmine 37-44 tumor protein p53 Homo sapiens 111-114