PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25250831-1 2015 Harmine is a naturally occurring monoamine oxidase inhibitor that has recently been shown to selectively inhibit the dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A (DYRK1A). Harmine 0-7 dual specificity tyrosine phosphorylation regulated kinase 1A Rattus norvegicus 117-182 25250831-1 2015 Harmine is a naturally occurring monoamine oxidase inhibitor that has recently been shown to selectively inhibit the dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A (DYRK1A). Harmine 0-7 dual specificity tyrosine phosphorylation regulated kinase 1A Rattus norvegicus 184-190 35623405-3 2022 This study aimed at evaluating the prophylactic effects of the dual-specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) inhibitor "harmine" against 3-NP-indued neurotoxicity and HD-like symptoms. Harmine 145-152 dual specificity tyrosine phosphorylation regulated kinase 1A Rattus norvegicus 63-124 35623405-3 2022 This study aimed at evaluating the prophylactic effects of the dual-specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) inhibitor "harmine" against 3-NP-indued neurotoxicity and HD-like symptoms. Harmine 145-152 dual specificity tyrosine phosphorylation regulated kinase 1A Rattus norvegicus 126-132 26067684-9 2015 Inversely, treatment of MI-induced HF rats with Dyrk1A inhibitor, either harmine or EGCG, improved the symptoms of HF, reversed the molecular changes of Dyrk1A and ASF, and regulated alternative splicing of CaMKIIdelta in HF rats. Harmine 73-80 dual specificity tyrosine phosphorylation regulated kinase 1A Rattus norvegicus 48-54 26067684-9 2015 Inversely, treatment of MI-induced HF rats with Dyrk1A inhibitor, either harmine or EGCG, improved the symptoms of HF, reversed the molecular changes of Dyrk1A and ASF, and regulated alternative splicing of CaMKIIdelta in HF rats. Harmine 73-80 dual specificity tyrosine phosphorylation regulated kinase 1A Rattus norvegicus 153-159