PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21573099-0 2011 beta-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer"s disease-related sites. Harmine 36-43 microtubule associated protein tau Homo sapiens 64-67 21573099-5 2011 Here we test the ability of harmine, and numerous additional beta-carboline compounds, to inhibit the DYRK1A dependent phosphorylation of tau protein on serine 396, serine 262/serine 356 (12E8 epitope), and threonine 231 in cell culture assays and in vitro phosphorylation assays. Harmine 28-35 microtubule associated protein tau Homo sapiens 138-141 27282658-4 2017 We identify the DYRK1A kinase inhibitor harmine, which phosphorylates Tau that is deregulated in Alzheimer"s disease, as a potentiator of cell death induced by non-toxic doses of doxorubicin. Harmine 40-47 microtubule associated protein tau Homo sapiens 70-73