PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24176842-0 2014 Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer. Harmine 0-7 prostaglandin-endoperoxide synthase 2 Homo sapiens 115-131 24176842-9 2014 In addition, harmine significantly inhibited the expression of COX-2, PCNA, Bcl-2 and MMP-2 as well as increased Bax expression in gastric cancer cells. Harmine 13-20 prostaglandin-endoperoxide synthase 2 Homo sapiens 63-68 24176842-10 2014 These results collectively indicate that harmine induces apoptosis and inhibits proliferation, migration and invasion of human gastric cancer cells, which may be mediated by down-regulation of COX-2 expression. Harmine 41-48 prostaglandin-endoperoxide synthase 2 Homo sapiens 193-198 26622726-0 2015 Paclitaxel combined with harmine inhibits the migration and invasion of gastric cancer cells through downregulation of cyclooxygenase-2 expression. Harmine 25-32 prostaglandin-endoperoxide synthase 2 Homo sapiens 119-135 27446381-0 2016 Harmine combined with paclitaxel inhibits tumor proliferation and induces apoptosis through down-regulation of cyclooxygenase-2 expression in gastric cancer. Harmine 0-7 prostaglandin-endoperoxide synthase 2 Homo sapiens 111-127