PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19632287-0	2009	Acute harmine administration induces antidepressive-like effects and increases BDNF levels in the rat hippocampus.	Harmine	6-13	brain-derived neurotrophic factor	Rattus norvegicus	79-83	
20686906-0	2010	Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus.	Harmine	26-33	brain-derived neurotrophic factor	Rattus norvegicus	84-88	
20686906-7	2010	Brain-derived neurotrophic factor (BDNF) hippocampal levels were assessed in imipramine and harmine-treated rats by ELISA sandwich assay.	Harmine	92-99	brain-derived neurotrophic factor	Rattus norvegicus	0-33	
20686906-8	2010	Interestingly, chronic administration of harmine at the higher doses (10 and 15 mg/kg), but not imipramine, increased BDNF protein levels in rat hippocampus.	Harmine	41-48	brain-derived neurotrophic factor	Rattus norvegicus	118-122	
19772900-6	2010	Interestingly, treatment with harmine reversed anhedonia, the increase of adrenal gland weight, normalized ACTH circulating levels and BDNF protein levels.	Harmine	30-37	brain-derived neurotrophic factor	Rattus norvegicus	135-139	
19632287-3	2009	The present study aims to compare the behavioral effects and the BDNF hippocampus levels of acute administration of harmine and imipramine in rats.	Harmine	116-123	brain-derived neurotrophic factor	Rattus norvegicus	65-69	
19632287-5	2009	Afterwards, hippocampal BDNF protein levels were assessed in imipramine- and harmine-treated rats by ELISA-sandwich assay.	Harmine	77-84	brain-derived neurotrophic factor	Rattus norvegicus	24-28	
19632287-7	2009	Acute administration of harmine at the higher dose, but not imipramine, increased BDNF protein levels in the rat hippocampus.	Harmine	24-31	brain-derived neurotrophic factor	Rattus norvegicus	82-86	
32425784-0	2020	Harmine Ameliorates Cognitive Impairment by Inhibiting NLRP3 Inflammasome Activation and Enhancing the BDNF/TrkB Signaling Pathway in STZ-Induced Diabetic Rats.	Harmine	0-7	brain-derived neurotrophic factor	Rattus norvegicus	103-107	
32425784-9	2020	Moreover, we found that harmine treatment enhanced BDNF and phosphorylated TrkB levels in both the cortex of STZ-induced diabetic rats and HG-treated cells.	Harmine	24-31	brain-derived neurotrophic factor	Rattus norvegicus	51-55	
32425784-10	2020	These data indicate that harmine mitigates cognitive impairment by inhibiting NLRP3 inflammasome activation and enhancing the BDNF/TrkB signaling pathway.	Harmine	25-32	brain-derived neurotrophic factor	Rattus norvegicus	126-130