PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8980395-0	1996	Acceleration of MRP-associated efflux of rhodamine 123 by genistein and related compounds.	Genistein	58-67	ATP binding cassette subfamily C member 1	Homo sapiens	16-19	
27033456-7	2016	ABCC1 induction by GNT in MDA-MB-231 cells modified neither drug efflux nor chemoresistance due to simultaneous acute inhibition of the transporter activity by GNT.	Genistein	19-22	ATP binding cassette subfamily C member 1	Homo sapiens	0-5	
18634814-3	2008	We showed that 24 h after a single dose treatment with genistein, resveratrol or bisphenol A, the expression of ATP-binding cassette transporters (the multidrug resistance or MDR, and the multidrug resistance associated proteins or MRP) uridine diphosphate-glucuronosyltransferases (UGT) and/or sulfotransferases (ST) involved in 17beta-estradiol elimination process were significantly modulated and that 17beta-estradiol cellular flow was modified.	Genistein	55-64	ATP binding cassette subfamily C member 1	Homo sapiens	232-235	
12532374-9	2003	These results therefore indicate that the flavonoids morin, chalcone, silymarin, phloretin, genistein, quercetin, biochanin A, and kaempferol can inhibit MRP1-mediated drug transport, effects that may involve binding interactions with MRP1, as well as modulation of GSH concentrations.	Genistein	92-101	ATP binding cassette subfamily C member 1	Homo sapiens	154-158	
12532374-9	2003	These results therefore indicate that the flavonoids morin, chalcone, silymarin, phloretin, genistein, quercetin, biochanin A, and kaempferol can inhibit MRP1-mediated drug transport, effects that may involve binding interactions with MRP1, as well as modulation of GSH concentrations.	Genistein	92-101	ATP binding cassette subfamily C member 1	Homo sapiens	235-239	
12373300-7	2002	MRP1 mediated efflux of CFDA was analysed in the presence of DHT, the known substrates genistein, probenecid, and the specific inhibitor MK-571.	Genistein	87-96	ATP binding cassette subfamily C member 1	Homo sapiens	0-4	
25741749-8	2015	Also, cellular glucuronidation of genistein (38.3% for MRP1, 32.3% for MRP3, and 31.1% for MRP4; p < 0.01) and apigenin (40.6% for MRP1, 32.4% for MRP3, and 34.6% for MRP4; p < 0.001) was markedly suppressed.	Genistein	34-43	ATP binding cassette subfamily C member 1	Homo sapiens	55-59	
25741749-8	2015	Also, cellular glucuronidation of genistein (38.3% for MRP1, 32.3% for MRP3, and 31.1% for MRP4; p < 0.01) and apigenin (40.6% for MRP1, 32.4% for MRP3, and 34.6% for MRP4; p < 0.001) was markedly suppressed.	Genistein	34-43	ATP binding cassette subfamily C member 1	Homo sapiens	134-138	
15004974-3	2003	The MDR phenotype of the tumors was determined by a change in doxorubicin intracellular accumulation under the action of the ABC-transporter(s)" inhibitors: verapamil and genistein (specific inhibitors of Pgp and MRP respectively) and sodium azide (an inhibitor of all energy-dependent ABC-transporters).	Genistein	171-180	ATP binding cassette subfamily C member 1	Homo sapiens	213-216	
11448450-3	2001	We now demonstrate that other inhibitors of MRP1-mediated drug transport (e.g. MK571, indomethacin, genistein, and nifedipine) deplete cellular glutathione in these leukaemia cells (>30% decrease; P < 0.01) while having no effect on the parental CCRF-CEM cells.	Genistein	100-109	ATP binding cassette subfamily C member 1	Homo sapiens	44-48	
8548874-9	1996	However, genistein, which is a specific inhibitor of multidrug resistance-associated protein (MRP), increased the THP remaining in the resistant cells, and the value was approximately equal to that of the control group in the sensitive cells.	Genistein	9-18	ATP binding cassette subfamily C member 1	Homo sapiens	94-97	
8909298-11	1996	Genistein, an MRP-specific modulating agent, and arsenate, a compound for which MRP has previously been reported to confer resistance, were also competitive inhibitors, with Ki values of 17 and 29 microM, respectively.	Genistein	0-9	ATP binding cassette subfamily C member 1	Homo sapiens	14-17	
8909298-11	1996	Genistein, an MRP-specific modulating agent, and arsenate, a compound for which MRP has previously been reported to confer resistance, were also competitive inhibitors, with Ki values of 17 and 29 microM, respectively.	Genistein	0-9	ATP binding cassette subfamily C member 1	Homo sapiens	80-83	
7945406-0	1994	Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells.	Genistein	26-35	ATP binding cassette subfamily C member 1	Homo sapiens	91-94