PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15492278-6	2004	In addition, some of the changes observed in SWB77 were opposite to those seen in methionine-dependent tumors, including expression of p21, TRAIL-R2, and TIEG.	Methionine	82-92	H3 histone pseudogene 16	Homo sapiens	135-138	
27255182-10	2016	Breast cancer cell lines MCF10A and MDA-MB-231 grown in methionine-restricted cysteine-depleted media for 24 h also up-regulated P21 and P27 gene expression, and MDA-MB-231 cells had decreased proliferation.	Methionine	56-66	H3 histone pseudogene 16	Homo sapiens	129-132	
15492278-8	2004	Western blot analysis confirmed that methionine stress caused the following: (a) a marked increase of GADD45alpha and gamma in the wt-p53 cell lines SWB61 and 40; (b) an increase in GADD34 and p21 protein in all of the methionine-dependent lines; and (c) the induction of MDA7 and phospho-p38 in DAOY and SWB39, consistent with marked transcriptional activation of the former under methionine stress.	Methionine	37-47	H3 histone pseudogene 16	Homo sapiens	193-196	
14532004-4	2003	Instead, the free amino group of the N-terminal methionine of p21 is a site for ubiquitinylation in vivo.	Methionine	48-58	H3 histone pseudogene 16	Homo sapiens	62-65	
6422257-8	1984	The p21 of v-Ha-ras and the 30K proteins from S. cerevisiae share methionine-labeled peptides as detected by two-dimensional tryptic peptide maps.	Methionine	66-76	H3 histone pseudogene 16	Homo sapiens	4-7	
11341037-6	2000	Methionine restriction led to accumulation of the cyclin-dependent kinase inhibitors p21 and p27, as determined by Western blot analysis, and inhibited the enzymatic activities of the cyclin-dependent kinases CDK2 and cdc2, as determined by an in vitro kinase assay: However, methionine restriction had little or no effect on CDK2 or cdc2 protein levels.	Methionine	0-10	H3 histone pseudogene 16	Homo sapiens	85-88	
8175645-9	1994	Furthermore, Cys-3-AMBA-Met and Cys-4-ABA-Met are true inhibitors of p21ras FTase since they are not farnesylated by this enzyme, in contrast to Cys-Val-Ile-Met, which inhibits the enzyme by acting as alternative substrate.	Methionine	24-27	H3 histone pseudogene 16	Homo sapiens	69-72	
3018922-5	1986	Using 35S-methionine incorporation, immunoprecipitation with anti-p21 monoclonal antibodies, SDS-PAGE and autoradiography, it was demonstrated that p21 synthesis was remarkably enhanced in 7402 cells as well as in transformed cells derived from both 7402 and PHC DNA.	Methionine	10-20	H3 histone pseudogene 16	Homo sapiens	148-151	
6092927-5	1984	The intracellular half-life of p21 proteins was determined by pulse-labeling and chasing in the presence of excess unlabeled methionine.	Methionine	125-135	H3 histone pseudogene 16	Homo sapiens	31-34