PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12021520-2	2002	methylcobalamin (Me-Cbl), the coenzymatically active form of vitamin B12 that acts as a cofactor for methionine synthase in the conversion of total homocysteine (tHcy) to methionine, with or without oral folic acid (FA) supplementation, on fasting tHcy levels in hemodialysis (HD) patients.	Methionine	101-111	Cbl proto-oncogene	Homo sapiens	20-23	
7694037-1	1993	Homocysteine and 5-CH3-tetrahydrofolate (5-CH3-THF) are converted to methionine and THF by the CH3-cobalamin (CH3-Cbl)-dependent enzyme methionine synthase.	Methionine	69-79	Cbl proto-oncogene	Homo sapiens	114-117	
7901104-3	1993	The latter requires CH3-Cbl and catalyzes the conversion of 5-CH3-tetrahydrofolate and homocysteine to tetrahydrofolate and methionine, respectively.	Methionine	124-134	Cbl proto-oncogene	Homo sapiens	24-27	
7694037-11	1993	In patients with cbl C and cbl D mutations, methionine levels remained low or low-normal at 8.3 to 15.6 mumol/L (normal, 13.3 to 42.7) despite betaine treatment.	Methionine	44-54	Cbl proto-oncogene	Homo sapiens	17-20	
7694037-11	1993	In patients with cbl C and cbl D mutations, methionine levels remained low or low-normal at 8.3 to 15.6 mumol/L (normal, 13.3 to 42.7) despite betaine treatment.	Methionine	44-54	Cbl proto-oncogene	Homo sapiens	27-30	
34998158-0	2022	The CBL-LSD1-CXCL8 axis regulates methionine metabolism in glioma.	Methionine	34-44	Cbl proto-oncogene	Homo sapiens	4-7	
34998158-10	2022	Taken together, these findings indicate that the CBL/LSD1/CXCL8 axis is a novel mechanistic connection linking between methionine metabolism, histone methylation and glycerophospholipid reprogramming in the tumor microenvironment.	Methionine	119-129	Cbl proto-oncogene	Homo sapiens	49-52	
20352340-2	2010	TC deficiency is a rare autosomal recessive disorder causing intracellular Cbl depletion, which in turn causes megaloblastic bone marrow failure, accumulation of homocysteine and methylmalonic acid, and methionine depletion.	Methionine	203-213	Cbl proto-oncogene	Homo sapiens	75-78	
30693532-4	2019	Methionine synthase catalyzes the methyl-Cbl dependent (re)methylation of homocysteine to methionine within the methionine cycle; a reaction required to produce this essential amino acid and generate S-adenosylmethionine, the most important cellular methyl-donor.	Methionine	90-100	Cbl proto-oncogene	Homo sapiens	41-44	
30693532-4	2019	Methionine synthase catalyzes the methyl-Cbl dependent (re)methylation of homocysteine to methionine within the methionine cycle; a reaction required to produce this essential amino acid and generate S-adenosylmethionine, the most important cellular methyl-donor.	Methionine	112-122	Cbl proto-oncogene	Homo sapiens	41-44	
30693532-8	2019	It also provides a description of folate-mediated one-carbon metabolism and its intersection with Cbl at the methionine cycle.	Methionine	109-119	Cbl proto-oncogene	Homo sapiens	98-101	
23415654-1	2013	Vitamin B12 (cobalamin, cbl) is a cofactor of methionine synthase (MTR) in the synthesis of methionine, the precursor of the universal methyl donor S-Adenosylmethionine (SAM), which is involved in epigenomic regulatory mechanisms.	Methionine	46-56	Cbl proto-oncogene	Homo sapiens	24-27	
32289469-2	2020	The endogenous synthesis of methionine is catalyzed by methionine synthase, which transfers the methyl group of 5-methyltetrahydrofolate (5-methylTHF) to homocysteine in the presence of vitamin B12 (cobalamin, cbl).	Methionine	28-38	Cbl proto-oncogene	Homo sapiens	210-213