PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2548490-4	1989	However, ethidium bromide and novobiocin, which are known to disrupt nucleosome structure, and VM-26 (teniposide), a specific inhibitor of topoisomerase II, induce changes in histone methylation patterns which, though less severe, are similar to those observed under cellular stress.	Teniposide	95-100	Topoisomerase 2	Drosophila melanogaster	139-155	
1662808-7	1991	The topoisomerase II inhibitor VM-26 induced the formation of stable covalent DNA-protein intermediates.	Teniposide	31-36	Topoisomerase 2	Drosophila melanogaster	4-20	
2548490-4	1989	However, ethidium bromide and novobiocin, which are known to disrupt nucleosome structure, and VM-26 (teniposide), a specific inhibitor of topoisomerase II, induce changes in histone methylation patterns which, though less severe, are similar to those observed under cellular stress.	Teniposide	102-112	Topoisomerase 2	Drosophila melanogaster	139-155	
3023886-1	1986	Similar to its inhibitory effect on mammalian DNA topoisomerase II, the cytotoxic drug VM26 (teniposide) also interferes with the breakage-reunion reaction of Drosophila melanogaster DNA topoisomerase II.	Teniposide	87-91	Topoisomerase 2	Drosophila melanogaster	50-66	
3023886-1	1986	Similar to its inhibitory effect on mammalian DNA topoisomerase II, the cytotoxic drug VM26 (teniposide) also interferes with the breakage-reunion reaction of Drosophila melanogaster DNA topoisomerase II.	Teniposide	87-91	Topoisomerase 2	Drosophila melanogaster	46-66	
3023886-1	1986	Similar to its inhibitory effect on mammalian DNA topoisomerase II, the cytotoxic drug VM26 (teniposide) also interferes with the breakage-reunion reaction of Drosophila melanogaster DNA topoisomerase II.	Teniposide	93-103	Topoisomerase 2	Drosophila melanogaster	50-66	
3023886-1	1986	Similar to its inhibitory effect on mammalian DNA topoisomerase II, the cytotoxic drug VM26 (teniposide) also interferes with the breakage-reunion reaction of Drosophila melanogaster DNA topoisomerase II.	Teniposide	93-103	Topoisomerase 2	Drosophila melanogaster	46-66	
3023886-2	1986	VM26 induces topoisomerase II-mediated DNA breakage in vitro and in cultured D. melanogaster cells presumably by stabilizing an enzyme-DNA cleavable complex.	Teniposide	0-4	Topoisomerase 2	Drosophila melanogaster	13-29