PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30354214-11 2018 Mechanistically, teniposide reduced vascular calcification by inactivating BMP2/(pi-Smad1/5/8 [mothers against decapentaplegic homolog 1, 5, and 8])/RUNX2 (runt-related transcription factor 2) axis in a p53-dependent manner. Teniposide 17-27 bone morphogenetic protein 2 Mus musculus 75-79 30354214-12 2018 Furthermore, activated miR-203-3p by teniposide functioned as a link between activated p53 expression and inhibited BMP2 expression in inhibition of calcification. Teniposide 37-47 bone morphogenetic protein 2 Mus musculus 116-120 30354214-13 2018 Conclusions- Our study demonstrates that teniposide reduces vascular calcification by regulating p53-(miR-203-3p)-BMP2 signaling pathway, which contributes to the antiatherogenic properties of Topo II inhibitors. Teniposide 41-51 bone morphogenetic protein 2 Mus musculus 114-118