PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31197245-0	2019	Mebendazole elicits potent antimyeloma activity by inhibiting the USP5/c-Maf axis.	Mebendazole	0-11	MAF bZIP transcription factor	Homo sapiens	71-76	
31197245-4	2019	It was found that mebendazole, a typical anthelmintic drug, preferentially induced apoptosis in c-Maf-expressing myeloma cells.	Mebendazole	18-29	MAF bZIP transcription factor	Homo sapiens	96-101	
31197245-6	2019	Further studies showed that the selective antimyeloma activity of mebendazole was associated with the inhibition of the USP5/c-Maf axis.	Mebendazole	66-77	MAF bZIP transcription factor	Homo sapiens	125-130	
31197245-7	2019	Mebendazole downregulated USP5 expression and disrupted the interaction between USP5 and c-Maf, thus leading to increased levels of c-Maf ubiquitination and subsequent c-Maf degradation.	Mebendazole	0-11	MAF bZIP transcription factor	Homo sapiens	89-94	
31197245-7	2019	Mebendazole downregulated USP5 expression and disrupted the interaction between USP5 and c-Maf, thus leading to increased levels of c-Maf ubiquitination and subsequent c-Maf degradation.	Mebendazole	0-11	MAF bZIP transcription factor	Homo sapiens	132-137	
31197245-7	2019	Mebendazole downregulated USP5 expression and disrupted the interaction between USP5 and c-Maf, thus leading to increased levels of c-Maf ubiquitination and subsequent c-Maf degradation.	Mebendazole	0-11	MAF bZIP transcription factor	Homo sapiens	132-137	
31197245-8	2019	Mebendazole inhibited c-Maf transcriptional activity, as confirmed by both luciferase assays and expression measurements of c-Maf downstream genes.	Mebendazole	0-11	MAF bZIP transcription factor	Homo sapiens	22-27	
31197245-8	2019	Mebendazole inhibited c-Maf transcriptional activity, as confirmed by both luciferase assays and expression measurements of c-Maf downstream genes.	Mebendazole	0-11	MAF bZIP transcription factor	Homo sapiens	124-129	
31197245-9	2019	In summary, this study identified mebendazole as a USP5/c-Maf inhibitor that could be developed as a novel antimyeloma agent.	Mebendazole	34-45	MAF bZIP transcription factor	Homo sapiens	56-61