PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35368048-4 2022 We have previously screened the Connectivity Map database to identify mebendazole as an anti-AML therapeutic targeting c-MYB. Mebendazole 70-81 MYB proto-oncogene, transcription factor Homo sapiens 119-124 29089643-4 2018 Here, we have used a c-MYB gene expression signature from MLL-rearranged AML to probe the Connectivity Map database and identified mebendazole as a c-MYB targeting drug. Mebendazole 131-142 MYB proto-oncogene, transcription factor Homo sapiens 21-26 29089643-4 2018 Here, we have used a c-MYB gene expression signature from MLL-rearranged AML to probe the Connectivity Map database and identified mebendazole as a c-MYB targeting drug. Mebendazole 131-142 MYB proto-oncogene, transcription factor Homo sapiens 148-153 29089643-5 2018 Mebendazole induces c-MYB degradation via the proteasome by interfering with the heat shock protein 70 (HSP70) chaperone system. Mebendazole 0-11 MYB proto-oncogene, transcription factor Homo sapiens 20-25 29089643-8 2018 In the context of widespread human use of mebendazole, our data indicate that mebendazole-induced c-MYB degradation represents a safe and novel therapeutic approach for AML. Mebendazole 42-53 MYB proto-oncogene, transcription factor Homo sapiens 98-103 29089643-8 2018 In the context of widespread human use of mebendazole, our data indicate that mebendazole-induced c-MYB degradation represents a safe and novel therapeutic approach for AML. Mebendazole 78-89 MYB proto-oncogene, transcription factor Homo sapiens 98-103