PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30065850-12 2018 These results indicate that tyramine released from RIM inhibits RME via SER-2 signaling. Tyramine 28-36 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 72-77 19896925-5 2010 Thymol and carvacrol were then tested and demonstrated to interact with TyrR in desensitizing SER-2 for tyramine activation in [Ca(2+)](i) mobilization assay, and in translocating SER-2 from membrane to cytoplasm in receptor internalization assay. Tyramine 104-112 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 94-99 15569254-3 2004 Membranes prepared from cells expressing either SER-2 or SER-2A bind [3H]lysergic acid diethylamide (LSD) in the low nanomolar range and exhibit highest affinity for tyramine. Tyramine 166-174 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 48-53 15569254-3 2004 Membranes prepared from cells expressing either SER-2 or SER-2A bind [3H]lysergic acid diethylamide (LSD) in the low nanomolar range and exhibit highest affinity for tyramine. Tyramine 166-174 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 57-62 15569254-6 2004 Pertussis toxin treatment reduces affinity for both tyramine and octopamine, especially for octopamine in membranes from cells expressing SER-2, suggesting that the conformation of the mid-region of the third intracellular loop is dictated by G-protein interactions and is responsible for the differential tyramine/octopamine affinities of the two isoforms. Tyramine 52-60 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 138-143 15569254-6 2004 Pertussis toxin treatment reduces affinity for both tyramine and octopamine, especially for octopamine in membranes from cells expressing SER-2, suggesting that the conformation of the mid-region of the third intracellular loop is dictated by G-protein interactions and is responsible for the differential tyramine/octopamine affinities of the two isoforms. Tyramine 306-314 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 138-143 15569254-8 2004 Tyramine, but not octopamine, also elevates Ca2+ levels in cells expressing SER-2 and to a lesser extent SER-2A. Tyramine 0-8 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 76-81 30065850-17 2018 Conclusion: We demonstrate that endogenous tyramine downregulates calcium levels in GABAergic RME motor neurons in the head via the tyramine receptor SER-2 during backward locomotion and omega turns. Tyramine 43-51 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 150-155 23565061-6 2013 Tyramine temporally coordinates the different phases of the escape response through the synaptic activation of the fast-acting ionotropic receptor, LGC-55, and extrasynaptic activation of the slow-acting metabotropic receptor, SER-2. Tyramine 0-8 G_PROTEIN_RECEP_F1_2 domain-containing protein;Tyramine receptor Ser-2 Caenorhabditis elegans 227-232