PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29417334-4 2018 It was revealed early on that selective, even irreversible inhibition of MAO-B is free from the severe side effect of the non-selective MAO inhibitors, the potentiation of tyramine, resulting in the so-called "cheese effect". Tyramine 172-180 monoamine oxidase B Homo sapiens 73-78 25017965-4 2014 We find that upon incubation with hydrogen peroxide or the MAO substrate tyramine myoblasts from patients upregulate MAO-B expression and display a significant rise in reactive oxygen species (ROS) levels, with concomitant mitochondrial depolarization. Tyramine 73-81 monoamine oxidase B Homo sapiens 117-122 27118978-7 2016 GST also inhibited hMAO-B tyramine oxidation and hydrogen peroxide production more than hMAO-A. Tyramine 26-34 monoamine oxidase B Homo sapiens 19-25 24720993-2 2014 The method is based on the inhibition of TOD that catalyzes the oxidation of tyramine substrate to produce aldehyde and hydrogen peroxide (H2O2). Tyramine 77-85 monoamine oxidase B Homo sapiens 41-44 1741773-8 1991 The ratio, MAO A molecular activity:MAO B molecular activity decreased in the order: serotonin (35:1) greater than tryptamine (12:1) greater than tyramine (3.3:1) greater than dopamine (2.4:1) greater than benzylamine (1:23). Tyramine 146-154 monoamine oxidase B Homo sapiens 36-41 16807522-1 2006 OBJECTIVES: The monoamine oxidase B (MAO-B) is an enzyme involved in metabolism of dopamine, benzylamine, phenylethylamine, tyramine and tryptamine. Tyramine 124-132 monoamine oxidase B Homo sapiens 16-35 16807522-1 2006 OBJECTIVES: The monoamine oxidase B (MAO-B) is an enzyme involved in metabolism of dopamine, benzylamine, phenylethylamine, tyramine and tryptamine. Tyramine 124-132 monoamine oxidase B Homo sapiens 37-42 12897643-0 2003 Pressor response to intravenous tyramine in healthy subjects after safinamide, a novel neuroprotectant with selective, reversible monoamine oxidase B inhibition. Tyramine 32-40 monoamine oxidase B Homo sapiens 130-149 10777699-3 2000 The MAO substrate tyramine induced tyrosine phosphorylation of Shc, ERK activation, and an increase in DNA synthesis in HEK 293 expressing MAO-B, but not in wild type HEK 293 cells, which do not express MAO. Tyramine 18-26 monoamine oxidase B Homo sapiens 139-144 10498294-5 1999 Our results showed that cell incubation with tyramine (50 micromol/l) led to a time-dependent H2O2 generation which was fully inhibited by MAO A (clorgyline and RO 41-1049) and MAO B (selegiline and RO 19-6327) inhibitors. Tyramine 45-53 monoamine oxidase B Homo sapiens 177-182 8695909-1 1996 Bacterial cells respond to monoamine compounds, such as tyramine, dopamine, octopamine, or norepinephrine, and induce the syntheses of tyramine oxidase encoded by tynA and monoamine oxidase encoded by maoA. Tyramine 56-64 monoamine oxidase B Homo sapiens 135-151 8390270-1 1993 The "cheese effect", potentiation of sympathomimetic action of indirectly acting amines such as tyramine, the main side effect of irreversible non-selective and selective monoamine oxidase (MAO) A inhibitors, has largely been eliminated in the new generation of reversible selective MAO-A and B and irreversible MAO-B inhibitors. Tyramine 96-104 monoamine oxidase B Homo sapiens 312-317 1609337-6 1992 The reversible inhibitors of monoamine oxidase A (RIMAs) are a group of drugs that, by producing inhibition selectively of monoamine oxidase A (MOA-A), still allow metabolism of tyramine by MAO-B. Tyramine 178-186 monoamine oxidase B Homo sapiens 190-195 21628600-3 2012 Tyramine challenge studies, conducted to characterize rasagiline selectivity for the MAO-B enzyme and tyramine sensitivity, demonstrate that rasagiline, when used at the recommended dose, is selective for MAO-B and is not associated with heightened tyramine sensitivity. Tyramine 0-8 monoamine oxidase B Homo sapiens 85-90 20445015-0 2010 Clinical pharmacology tyramine challenge study to determine the selectivity of the monoamine oxidase type B (MAO-B) inhibitor rasagiline. Tyramine 22-30 monoamine oxidase B Homo sapiens 83-107 19006188-0 2010 Selective MAO-B inhibitors have low potential for the tyramine effect. Tyramine 54-62 monoamine oxidase B Homo sapiens 10-15 18678789-2 2008 Rasagiline mesylate is a novel irreversible selective monoamine oxidase type B inhibitor for Parkinson disease that may have a low risk of interaction with dietary tyramine because of its selectivity. Tyramine 164-172 monoamine oxidase B Homo sapiens 54-78 11259630-1 2001 The human monoamine oxidase (MAO) B plays a major role in the degradation of biogenic and dietary amines such as phenylethylamine, benzylamine, dopamine, and tyramine. Tyramine 158-166 monoamine oxidase B Homo sapiens 10-35 9572675-3 1998 Platelet MAO-B activity was measured using [14C]tyramine as substrate. Tyramine 48-56 monoamine oxidase B Homo sapiens 9-14 8573115-3 1996 Moreover the enzymatic activity of MAO-B towards phenylethylamine and tyramine is also suppressed after this immunoprecipitation, contrary to the MAO-A activity towards 5-hydroxy-tryptamine. Tyramine 70-78 monoamine oxidase B Homo sapiens 35-40 7955818-1 1994 The effects of monoamine oxidase B (MAO-B) inhibition by mofegiline on the pharmacokinetics of p-tyramine and its major metabolite, p-hydroxyphenylacetic acid, were investigated in 24 healthy male volunteers. Tyramine 95-105 monoamine oxidase B Homo sapiens 36-41 1759390-6 1991 After selective inhibition of MAO-A by chlorgyline the order of MAO-B-dependent effects of biogenic amines on mitochondrial enzymes studied was as follows: tyramine greater than or equal to 2-phenylethylamine much greater than serotonin. Tyramine 156-164 monoamine oxidase B Homo sapiens 64-69 6627826-9 1983 This may reflect the dose of cimoxatone used, the activity of monoamine oxidase form B (MAO-B) in the gut and liver or displacement of the predominantly reversible and predominantly competitive inhibitor, cimoxatone, from the enzyme by a high local tyramine concentration. Tyramine 249-257 monoamine oxidase B Homo sapiens 88-93 22282124-7 1991 The MAO-B inhibitor, selegiline (5 mg once daily), also lowered the oral tyramine threshold significantly. Tyramine 73-81 monoamine oxidase B Homo sapiens 4-9 3928010-4 1985 The pressor responses to tyramine were potentiated by the selective MAO-A inhibitor clorgyline (2 mg kg-1) but not by selegiline (1.0 mg kg-1) and AGN 1135 (1.5 mg kg-1), selective MAO-B inhibitors. Tyramine 25-33 monoamine oxidase B Homo sapiens 181-186 2153484-1 1990 In this rapid, simple, and convenient enzymatic method for measurement of tyrosine in plasma, tyrosine is converted to tyramine by action of tyrosine decarboxylase (EC 4.1.1.25) and the tyramine produced is oxidized to p-hydroxybenzyl aldehyde and hydrogen peroxide by action of tyramine oxidase (EC 1.4.3.9). Tyramine 119-127 monoamine oxidase B Homo sapiens 279-295 2153484-1 1990 In this rapid, simple, and convenient enzymatic method for measurement of tyrosine in plasma, tyrosine is converted to tyramine by action of tyrosine decarboxylase (EC 4.1.1.25) and the tyramine produced is oxidized to p-hydroxybenzyl aldehyde and hydrogen peroxide by action of tyramine oxidase (EC 1.4.3.9). Tyramine 186-194 monoamine oxidase B Homo sapiens 279-295 34784871-11 2021 Of monoamine oxidase B inhibitors, safinamide is the least susceptible for interaction with the tyramine-rich food, whereas selegiline and rasagiline may lose selectivity to monoamine oxidase B when administered in supratherapeutic doses. Tyramine 96-104 monoamine oxidase B Homo sapiens 3-22 2503040-4 1989 The presence of MAO-B was corroborated by the inhibition of PEA oxidation with nanomolar deprenyl concentrations and by inhibition of TYR oxidation with high clorgyline concentrations, as well as by the simple sigmoid curve obtained in both cases. Tyramine 134-137 monoamine oxidase B Homo sapiens 16-21 3266532-3 1988 Brain selectivity would overcome the risk of tyramine interactions which have been shown to occur with selective MAO-A but not MAO-B inhibitors. Tyramine 45-53 monoamine oxidase B Homo sapiens 127-132 6791202-4 1981 The effects of treatment with the selective MAO-A inhibitor clorgyline and the partially selective MAO-B inhibitors pargyline and deprenyl on tyramine"s pressor effects were studied in depressed patients using an IV steady-state tyramine infusion technique. Tyramine 142-150 monoamine oxidase B Homo sapiens 99-104 6791210-7 1981 Tyramine pressor sensitivity changes accompanying administration of the MAO inhibitors were highly correlated with decreases in plasma MHPG (r = 0.92), supporting our previous data indicating the rank order of clorgyline greater than pargyline greater than deprenyl for enhancement of tyramine pressor sensitivity and, thus, suggesting that tyramine potentiation is primarily a function of MAO-A rather than MAO-B inhibition. Tyramine 0-8 monoamine oxidase B Homo sapiens 408-413 32942081-1 2020 Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine, serotonin, and some other amines. Tyramine 165-173 monoamine oxidase B Homo sapiens 30-35 33992221-4 2021 Previously, these Q-TAO strips have been also optimized for tyramine determination in cheese extract. Tyramine 60-68 monoamine oxidase B Homo sapiens 20-23 32072299-3 2020 Tyramine has been determined using its enzymatic reaction with tyramine oxidase (TAO). Tyramine 0-8 monoamine oxidase B Homo sapiens 63-79 32072299-3 2020 Tyramine has been determined using its enzymatic reaction with tyramine oxidase (TAO). Tyramine 0-8 monoamine oxidase B Homo sapiens 81-84 32072299-9 2020 Graphical abstractTyramine is determined by measuring the plasmon band of the gold nanoparticles formed during its enzymatic reaction with Tyramine oxidase. Tyramine 18-26 monoamine oxidase B Homo sapiens 139-155