PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17561096-3	2007	Incubation of SMC with serotonin or tyramine induced intracellular ROS generation, and a signaling cascade involving metalloproteases and the neutral sphingomyelinase-2 (nSMase2, the initial step of the sphingolipid pathway), ERK1/2 phosphorylation, and DNA synthesis.	Tyramine	36-44	sphingomyelin phosphodiesterase 3	Homo sapiens	142-168	
17561096-3	2007	Incubation of SMC with serotonin or tyramine induced intracellular ROS generation, and a signaling cascade involving metalloproteases and the neutral sphingomyelinase-2 (nSMase2, the initial step of the sphingolipid pathway), ERK1/2 phosphorylation, and DNA synthesis.	Tyramine	36-44	sphingomyelin phosphodiesterase 3	Homo sapiens	170-177	
17561096-6	2007	Silencing nSMase2 by siRNA did not inhibit ROS generation and MMP2 activation, but blocked SMC proliferation induced by tyramine, suggesting that nSMase2 is downstream MMP2.	Tyramine	120-128	sphingomyelin phosphodiesterase 3	Homo sapiens	10-17