PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27828941-4 2016 Tyramine and octopamine released from neurons expressing tyrosine decarboxylase 2 (Tdc2) signal directly to astrocytes to stimulate Ca2+ increases through the octopamine/tyramine receptor (Oct-TyrR) and the transient receptor potential (TRP) channel Water witch (Wtrw), and astrocytes in turn modulate downstream dopaminergic neurons. Tyramine 0-8 Octopamine-Tyramine receptor Drosophila melanogaster 189-197 27828941-5 2016 Application of tyramine or octopamine to live preparations silenced dopaminergic neurons and this inhibition required astrocytic Oct-TyrR and Wtrw. Tyramine 15-23 Octopamine-Tyramine receptor Drosophila melanogaster 129-137 27828941-8 2016 Our work identifies Oct-TyrR and Wtrw as key components of the astrocytic Ca2+ signalling machinery, provides direct evidence that octopamine- and tyramine-based neuromodulation can be mediated by astrocytes, and demonstrates that astrocytes are essential for multiple sensory-driven behaviours in Drosophila. Tyramine 147-155 Octopamine-Tyramine receptor Drosophila melanogaster 20-28 6122719-4 1982 Tyramine, norepinephrine, and epinephrine also stimulate the cyclase, probably via the octopamine receptor. Tyramine 0-8 Octopamine-Tyramine receptor Drosophila melanogaster 87-106