PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17632001-1	2007	Starting from a biased needle screening hit 3a, we report herein the design and synthesis of a series of novel 2,3-dihydroisoindol-1-ones structurally related to cyclothialidine 2 with DNA gyrase inhibitory activity.	2,3-dihydroisoindol-1-ones	111-137	DNA topoisomerase II alpha	Homo sapiens	185-195