PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22396165-4	2012	Removal of terminal sialic acids from N-glycan chains of the epithelial Ca(2+) channel TRPV5 and the renal K(+) channel ROMK by secreted Klotho exposes the underlying disaccharide galactose-N-acetylglucosamine, a ligand for galectin-1.	n-glycan	38-46	klotho	Homo sapiens	137-143	
25378396-3	2014	Secreted Klotho (sKL) up-regulates the TRPV5 calcium channel from the cell exterior by removing sialic acids from N-glycan of the channel and inhibiting its endocytosis.	n-glycan	114-122	klotho	Homo sapiens	9-15	
23970553-5	2013	Klotho was found to increase the plasma membrane stability of TRPV5, via the TRPV5 N-glycan.	n-glycan	83-91	klotho	Homo sapiens	0-6	
23970553-10	2013	Previous studies showed that after klotho treatment, galectin-1 binds the TRPV5 N-glycan and thereby increases TRPV5 activity.	n-glycan	80-88	klotho	Homo sapiens	35-41	
23970553-13	2013	In conclusion, two distinct TRPV5 stimulatory mechanisms were demonstrated; a klotho-mediated effect that is dependent on the N-glycan of TRPV5 and a sialidase-mediated stimulation that is lipid raft-dependent and independent of the N-glycan of TRPV5.	n-glycan	126-134	klotho	Homo sapiens	78-84