PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8702436-1	1996	OBJECTIVE: To evaluate the effects of the phospholipase A2 (PLA2) inhibitor manoalide on cartilage degradation, stromelysin expression, and inflammatory cell accumulation in rabbits treated intraarticularly with recombinant human interleukin-1 alpha (rHuIL-1 alpha).	manoalide	76-85	phospholipase A2	Oryctolagus cuniculus	60-64	
8702436-11	1996	Pretreatment with manoalide (0.3 mg/joint) significantly inhibited PLA2 activity in the synovial fluid, prevented the loss of proteoglycan from the condylar cartilage, and reduced proteoglycan levels in lavage fluids.	manoalide	18-27	phospholipase A2	Oryctolagus cuniculus	67-71	
8702436-15	1996	CONCLUSION: These studies demonstrate that manoalide is a potent inhibitor of inflammation and cartilage catabolism, and suggest that PLA2 is involved in the pathophysiology of rHuIL-1 alpha-induced arthritis in rabbits.	manoalide	43-52	phospholipase A2	Oryctolagus cuniculus	134-138	
2640487-2	1989	Manoalide inhibits phospholipase A2 from extracellular sources (snake venoms, bee, etc.	manoalide	0-9	phospholipase A2	Oryctolagus cuniculus	19-35	
3026352-6	1986	Release of arachidonic acid is probably via phospholipase A2, since it is blocked by the phospholipase A2 inhibitor manoalide.	manoalide	116-125	phospholipase A2	Oryctolagus cuniculus	44-60	
3026352-6	1986	Release of arachidonic acid is probably via phospholipase A2, since it is blocked by the phospholipase A2 inhibitor manoalide.	manoalide	116-125	phospholipase A2	Oryctolagus cuniculus	89-105	
2827828-0	1987	The inhibition of release of endothelium-derived relaxant factor by manoalide, a potent inhibitor of phospholipase A2.	manoalide	68-77	phospholipase A2	Oryctolagus cuniculus	101-117